|
1
|
Third Rock Ventures
Boston,
Massachusetts
|
$428M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$142M
|
+$451K
|
+12,104
|
+0.3%
|
|
|
3
|
BlackRock Fund Advisors
San Francisco,
California
|
$16.9M
|
+$11.9M
|
+320,341
|
+226%
|
|
|
4
|
|
$15.1M
|
-$4.66M
|
-125,000
|
-23%
|
|
|
5
|
RS Investment Management
San Francisco,
California
|
$13M
|
+$2.42M
|
+64,958
|
+22%
|
|
|
6
|
Deerfield Management
New York
|
$9.61M
|
-$7.01M
|
-188,042
|
-42%
|
|
|
7
|
AllianceBernstein
Nashville,
Tennessee
|
$9.14M
|
-$193K
|
-5,186
|
-2%
|
|
|
8
|
EcoR1 Capital
San Francisco,
California
|
$9.07M
|
+$18.3M
|
+491,044
|
New
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$8.15M
|
+$7.09M
|
+190,220
|
+585%
|
|
|
10
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$7.47M
|
–
|
–
|
–
|
|
|
11
|
Franklin Resources
San Mateo,
California
|
$7.32M
|
–
|
–
|
–
|
|
|
12
|
|
$6.52M
|
+$4.45M
|
+119,296
|
+203%
|
|
|
13
|
Stifel Financial
St. Louis,
Missouri
|
$5.72M
|
+$3.74M
|
+100,261
|
New
|
|
|
14
|
Foresite Capital Management II
Larkspur,
California
|
$5.29M
|
+$5.39M
|
+144,569
|
New
|
|
|
15
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$3.96M
|
+$4.03M
|
+108,226
|
New
|
|
|
16
|
Sphera Funds Management
Tel Aviv,
Israel
|
$2.92M
|
-$306K
|
-8,200
|
-9%
|
|
|
17
|
Baker Bros. Advisors
New York
|
$2.75M
|
–
|
–
|
–
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$2.67M
|
+$923K
|
+24,772
|
+52%
|
|
|
19
|
Perceptive Advisors
New York
|
$2.58M
|
-$5.15M
|
-138,192
|
-66%
|
|
|
20
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$2.39M
|
+$37.3K
|
+1,001
|
+2%
|
|
|
21
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$2.38M
|
+$2.42M
|
+65,000
|
New
|
|
|
22
|
BlackRock Advisors
Wilmington,
Delaware
|
$2.28M
|
+$914K
|
+24,526
|
+65%
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$2.15M
|
+$1.67M
|
+44,704
|
+321%
|
|
|
24
|
BlackRock Institutional Trust
San Francisco,
California
|
$2.02M
|
+$58.1K
|
+1,559
|
+3%
|
|
|
25
|
Citadel Advisors
Miami,
Florida
|
$1.99M
|
+$500K
|
+13,425
|
+33%
|
|
