|
1
|
Third Rock Ventures
Boston,
Massachusetts
|
$368M
|
+$338M
|
+11,681,008
|
New
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$121M
|
+$112M
|
+3,856,789
|
New
|
|
|
3
|
|
$16.9M
|
+$15.6M
|
+537,335
|
New
|
|
|
4
|
Deerfield Management
New York
|
$14.2M
|
+$13.1M
|
+450,667
|
New
|
|
|
5
|
RS Investment Management
San Francisco,
California
|
$9.11M
|
+$8.38M
|
+289,100
|
New
|
|
|
6
|
AllianceBernstein
Nashville,
Tennessee
|
$8.03M
|
+$7.38M
|
+254,852
|
New
|
|
|
7
|
Perceptive Advisors
New York
|
$6.57M
|
+$6.05M
|
+208,676
|
New
|
|
|
8
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$6.43M
|
+$5.92M
|
+204,200
|
New
|
|
|
9
|
Franklin Resources
San Mateo,
California
|
$6.3M
|
+$5.8M
|
+200,000
|
New
|
|
|
10
|
BlackRock Fund Advisors
San Francisco,
California
|
$4.46M
|
+$4.1M
|
+141,607
|
New
|
|
|
11
|
Alyeska Investment Group
Chicago,
Illinois
|
$3.14M
|
+$2.89M
|
+99,674
|
New
|
|
|
12
|
Sphera Funds Management
Tel Aviv,
Israel
|
$2.77M
|
+$2.55M
|
+87,924
|
New
|
|
|
13
|
Millennium Management
New York
|
$2.52M
|
+$2.32M
|
+80,078
|
New
|
|
|
14
|
Baker Bros. Advisors
New York
|
$2.36M
|
+$2.17M
|
+75,000
|
New
|
|
|
15
|
Nicholas Investment Partners
Rancho Santa Fe,
California
|
$2.02M
|
+$1.86M
|
+64,185
|
New
|
|
|
16
|
|
$1.85M
|
+$1.7M
|
+58,775
|
New
|
|
|
17
|
|
$1.83M
|
+$1.68M
|
+58,136
|
New
|
|
|
18
|
BlackRock Institutional Trust
San Francisco,
California
|
$1.69M
|
+$1.55M
|
+53,644
|
New
|
|
|
19
|
State Street
Boston,
Massachusetts
|
$1.51M
|
+$1.39M
|
+48,100
|
New
|
|
|
20
|
Citadel Advisors
Miami,
Florida
|
$1.29M
|
+$1.19M
|
+41,037
|
New
|
|
|
21
|
Eventide Asset Management
Boston,
Massachusetts
|
$1.27M
|
+$1.16M
|
+40,200
|
New
|
|
|
22
|
BlackRock Advisors
Wilmington,
Delaware
|
$1.19M
|
+$1.09M
|
+37,750
|
New
|
|
|
23
|
|
$1.18M
|
+$1.09M
|
+37,600
|
New
|
|
|
24
|
Vanguard Group
Malvern,
Pennsylvania
|
$1.02M
|
+$942K
|
+32,525
|
New
|
|
|
25
|
Bank of New York Mellon
New York
|
$901K
|
+$829K
|
+28,595
|
New
|
|
