|
1
|
|
$84.4M
|
+$7.19M
|
+375,784
|
+8%
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$84.4M
|
-$51.9M
|
-2,714,102
|
-34%
|
|
|
3
|
|
$67.3M
|
+$3.63M
|
+189,975
|
+5%
|
|
|
4
|
Cowen and Company
New York
|
$61.9M
|
+$29.2M
|
+1,524,216
|
+67%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$56.7M
|
-$6.44M
|
-336,804
|
-9%
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$47.3M
|
+$2.67M
|
+139,780
|
+5%
|
|
|
7
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$45.3M
|
+$53.1M
|
+2,775,292
|
New
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$44.1M
|
+$5.28M
|
+276,254
|
+11%
|
|
|
9
|
Avidity Partners Management
Dallas,
Texas
|
$42.5M
|
+$9.94M
|
+519,800
|
+25%
|
|
|
10
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$40.5M
|
+$67K
|
+3,500
|
+0.1%
|
|
|
11
|
RA Capital Management
Boston,
Massachusetts
|
$35.4M
|
–
|
–
|
–
|
|
|
12
|
Cormorant Asset Management
Boston,
Massachusetts
|
$32.9M
|
–
|
–
|
–
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$28.7M
|
-$1.48M
|
-77,344
|
-4%
|
|
|
14
|
Avoro Capital Advisors
New York
|
$23.7M
|
+$2.87M
|
+150,000
|
+12%
|
|
|
15
|
Boxer Capital
San Diego,
California
|
$18.3M
|
–
|
–
|
–
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$15.3M
|
+$1.74M
|
+90,923
|
+11%
|
|
|
17
|
Alethea Capital Management
Mercer Island,
Washington
|
$13.6M
|
–
|
–
|
–
|
|
|
18
|
Dimensional Fund Advisors
Austin,
Texas
|
$10.8M
|
+$2.87M
|
+149,768
|
+29%
|
|
|
19
|
|
$10.1M
|
+$8.33M
|
+435,617
|
+238%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$7.85M
|
+$459K
|
+23,994
|
+5%
|
|
|
21
|
Artisan Partners
Milwaukee,
Wisconsin
|
$6.38M
|
-$46.2K
|
-2,413
|
-0.6%
|
|
|
22
|
5AM Venture Management
San Francisco,
California
|
$6.38M
|
–
|
–
|
–
|
|
|
23
|
Octagon Capital Advisors
New York
|
$6.2M
|
+$1.11M
|
+57,988
|
+18%
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$6.16M
|
+$758K
|
+39,639
|
+12%
|
|
|
25
|
|
$4.42M
|
-$26.8K
|
-1,399
|
-0.5%
|
|
