Regenxbio
RGNX
174 hedge funds and large institutions have $593M invested in Regenxbio in 2025 Q4 according to their latest regulatory filings, with 24 funds opening new positions, 62 increasing their positions, 60 reducing their positions, and 14 closing their positions.
71% more first-time investments, than exits
New positions opened: 24 | Existing positions closed: 14
49% more capital invested
Capital invested by funds: $399M → $593M (+$194M)
5% more funds holding
Funds holding: 166 → 174 (+8)
8% more call options, than puts
Call options by funds: $2.83M | Put options by funds: $2.62M
3% more repeat investments, than reductions
Existing positions increased: 62 | Existing positions reduced: 60
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
0.6% less ownership
Funds ownership: 81.88% → 81.28% (-0.6%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Assenagon Asset Management
Senningerberg,
Luxembourg
|
+$5.67M |
| 2 |
Morgan Stanley
New York
|
+$3.87M |
| 3 |
State Street
Boston,
Massachusetts
|
+$3.76M |
| 4 |
PFCS
Pale Fire Capital SE
Prague,
Czech Republic
|
+$3.04M |
| 5 |
Qube Research & Technologies (QRT)
London,
United Kingdom
|
+$1.97M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
BlackRock
New York
|
-$7.65M |
| 2 |
JP Morgan Chase
New York
|
-$6.03M |
| 3 |
ICM
Invenomic Capital Management
Boston,
Massachusetts
|
-$4.12M |
| 4 |
RG
Redmile Group
San Francisco,
California
|
-$4.05M |
| 5 |
VC
Voss Capital
Houston,
Texas
|
-$2.56M |
RGNX Hedge Fund Activity: Q4 2025 in Review
174 of the 8,270 institutional investors tracked by Wall St. Rank reported a position in Regenxbio (RGNX) for Q4 2025, worth a combined $593M — up 49% from $399M a quarter earlier.
Buyers outnumbered sellers: 24 funds opened new RGNX positions and 14 closed out — a net gain of 10 holders — while 62 added to existing stakes and 60 trimmed.
The largest buyer was Assenagon Asset Management, adding an estimated $5.67M. The largest seller was BlackRock, cutting an estimated $7.65M.
- 174 institutional investors held Regenxbio (RGNX) as of Q4 2025, up from 166 in Q3 2025.
- Funds reported $593M of Regenxbio stock for Q4 2025, up 49% quarter-over-quarter.
- 24 funds opened new Regenxbio positions in Q4 2025 and 14 closed out, a net change of +10 holders.
- The largest Regenxbio buyer in Q4 2025 was Assenagon Asset Management, an estimated $5.67M added.
- The largest Regenxbio seller in Q4 2025 was BlackRock, an estimated $7.65M sold.
Based on aggregated 13F filings for Q4 2025.