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Repligen
RGEN

441 hedge funds and large institutions have $7.76B invested in Repligen in 2026 Q1 according to their latest regulatory filings, with 67 funds opening new positions, 165 increasing their positions, 131 reducing their positions, and 91 closing their positions.

New
Increased
Maintained
Reduced
Closed

26% more repeat investments, than reductions

Existing positions increased: 165 | Existing positions reduced: 131

5.38% more ownership

Funds ownership: 110.91% → 116.29% (+5.4%)

7% less funds holding

Funds holding: 473 → 441 (-32)

24% less capital invested

Capital invested by funds: $10.2B → $7.76B (-$2.48B)

25% less funds holding in top 10

Funds holding in top 10: 8 → 6 (-2)

26% less first-time investments, than exits

New positions opened: 67 | Existing positions closed: 91

46% less call options, than puts

Call options by funds: $24.5M | Put options by funds: $45.7M

Holders
441
Holders Change
-32
Holders Change %
-6.77%
% of All Funds
5.43%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.07%
New
67
Increased
165
Reduced
131
Closed
91
Calls
$24.5M
Puts
$45.7M
Net Calls
-$21.2M
Net Calls Change
+$15.5M

Top Buyers

Rank Fund Capital Flow
1
MC
Maverick Capital
Texas
+$212M
2
WA
Wasatch Advisors
Utah
+$174M
3
VPC
Vestal Point Capital
New York
+$118M
4
T. Rowe Price Investment Management
T. Rowe Price Investment Management
Maryland
+$101M
5
Ameriprise
Ameriprise
Minnesota
+$60.2M

Top Sellers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
-$87.7M
2
BlackRock
BlackRock
New York
-$87.5M
3
Marshall Wace
Marshall Wace
United Kingdom
-$84.6M
4
Walleye Capital
Walleye Capital
New York
-$68.3M
5
FAM
Fred Alger Management
New York
-$66.6M
Name Holding Trade Value Shares
Change 		Change in
Stake
Bank of Montreal
151
Bank of Montreal
Ontario, Canada
$2.79M +$727K +5,207 +28%
State of Tennessee, Department of Treasury
152
State of Tennessee, Department of Treasury
Tennessee
$2.73M – – –
Treasurer of the State of North Carolina
153
Treasurer of the State of North Carolina
North Carolina
$2.66M +$66.5K +476 +2%
Millennium Management
154
Millennium Management
New York
$2.65M -$87.7M -628,085 -97%
PFSRSONJ
155
Police & Firemen's Retirement System of New Jersey
New Jersey
$2.62M – – –
Bank of Nova Scotia
156
Bank of Nova Scotia
Ontario, Canada
$2.59M -$3.14M -22,460 -50%
VGA
157
Vanguard Global Advisers
Pennsylvania
$2.55M +$3.02M +21,613 New
DIM
158
Delta Investment Management
California
$2.49M -$332K -2,380 -10%
KF
159
Krilogy Financial
Missouri
$2.49M +$1.23M +8,801 +82%
Pathstone Holdings
160
Pathstone Holdings
New Jersey
$2.48M -$451K -3,228 -13%
RHJA
161
Rice Hall James & Associates
California
$2.37M -$54.9K -393 -2%
Handelsbanken Fonder
162
Handelsbanken Fonder
Sweden
$2.33M +$142K +1,019 +5%
HSBC Holdings
163
HSBC Holdings
United Kingdom
$2.31M +$2.47M +17,679 +845%
BFM
164
Boothbay Fund Management
New York
$2.26M +$2.68M +19,198 New
State of New Jersey Common Pension Fund D
165
State of New Jersey Common Pension Fund D
New Jersey
$2.25M +$38K +272 +1%
JIC
166
Johnson Investment Counsel
Ohio
$2.24M +$68.7K +492 +3%
US Bancorp
167
US Bancorp
Minnesota
$2.22M +$652K +4,665 +33%
AIP
168
Ameritas Investment Partners
Nebraska
$2.18M +$530K +3,791 +26%
CCM
169
Cinctive Capital Management
New York
$2.16M +$1.49M +10,696 +140%
Commonwealth Equity Services
170
Commonwealth Equity Services
Massachusetts
$2.14M +$1.68M +12,044 +196%
BMSSC
171
B. Metzler seel. Sohn & Co
Germany
$2.03M +$1.3M +9,280 +116%
IIM
172
INTECH Investment Management
Florida
$1.96M +$1.82M +13,048 +360%
LCM
173
Legato Capital Management
California
$1.94M -$511K -3,655 -18%
LSERS
174
Louisiana State Employees Retirement System
Louisiana
$1.8M +$97.8K +700 +5%
ASRS
175
Arizona State Retirement System
Arizona
$1.73M -$24.4K -175 -1%
5 6
7
8 9

RGEN Hedge Fund Activity: Q1 2026 in Review

441 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Repligen (RGEN) for Q1 2026, worth a combined $7.76B — down 24% from $10.2B a quarter earlier.

Sellers outnumbered buyers: 91 funds closed out of RGEN and 67 opened new positions — a net loss of 24 holders — while 131 trimmed existing stakes and 165 added.

The largest buyer was Maverick Capital, opening a new position worth an estimated $212M. The largest seller was Millennium Management, cutting an estimated $87.7M.

  • 441 institutional investors held Repligen (RGEN) as of Q1 2026, down from 473 in Q4 2025.
  • Funds reported $7.76B of Repligen stock for Q1 2026, down 24% quarter-over-quarter.
  • 67 funds opened new Repligen positions in Q1 2026 and 91 closed out, a net change of -24 holders.
  • The largest Repligen buyer in Q1 2026 was Maverick Capital, an estimated $212M added.
  • The largest Repligen seller in Q1 2026 was Millennium Management, an estimated $87.7M sold.

Based on aggregated 13F filings for Q1 2026.