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Replimune Group
REPL

180 hedge funds and large institutions have $619M invested in Replimune Group in 2026 Q1 according to their latest regulatory filings, with 47 funds opening new positions, 61 increasing their positions, 49 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

213% more call options, than puts

Call options by funds: $46.8M | Put options by funds: $14.9M

62% more first-time investments, than exits

New positions opened: 47 | Existing positions closed: 29

24% more repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 49

10% more funds holding

Funds holding: 164 → 180 (+16)

0% more funds holding in top 10

Funds holding in top 10: 2 → 2 (0)

3.45% less ownership

Funds ownership: 101.66% → 98.21% (-3.4%)

20% less capital invested

Capital invested by funds: $775M → $619M (-$156M)

Holders
180
Holders Change
+16
Holders Change %
+9.76%
% of All Funds
2.22%
Holding in Top 10
2
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
47
Increased
61
Reduced
49
Closed
29
Calls
$46.8M
Puts
$14.9M
Net Calls
+$31.9M
Net Calls Change
-$6.23M

Top Buyers

Rank Fund Capital Flow
1
SCM
Suvretta Capital Management
New York
+$32M
2
Goldman Sachs
Goldman Sachs
New York
+$12.4M
3
EC
EcoR1 Capital
California
+$7.64M
4
SCM
Sio Capital Management
New York
+$5.5M
5
BCM
Boxer Capital Management
California
+$3.25M

Top Sellers

Rank Fund Capital Flow
1
CC
Commodore Capital
New York
-$13.9M
2
Adage Capital Partners
Adage Capital Partners
Massachusetts
-$11.5M
3
RA
Rosalind Advisors
Ontario, Canada
-$10.8M
4
RG
Redmile Group
California
-$10.7M
5
Fidelity Investments
Fidelity Investments
Massachusetts
-$7.16M
Name Holding Trade Value Shares
Change 		Change in
Stake
UBS Group
26
UBS Group
Switzerland
$4.45M -$177K -23,103 -4%
VPM
27
Vanguard Portfolio Management
Pennsylvania
$4.23M +$4.22M +552,576 New
VFT
28
Vanguard Fiduciary Trust
Pennsylvania
$3.63M +$3.63M +475,126 New
CM
29
Caption Management
Oklahoma
$3.46M +$1.71M +223,252 +98%
Jane Street
30
Jane Street
New York
$3.28M -$1.19M -156,185 -27%
Citadel Advisors
31
Citadel Advisors
Florida
$3.05M +$1.84M +240,370 +152%
CS
32
Candriam SCA
Luxembourg
$3.01M +$3.01M +394,027 New
Renaissance Technologies
33
Renaissance Technologies
New York
$2.92M -$180K -23,600 -6%
WP
34
Woodline Partners
California
$2.91M -$1.45M -190,000 -33%
Two Sigma Investments
35
Two Sigma Investments
New York
$2.64M -$759K -99,323 -22%
EP
36
Eversept Partners
New York
$2.56M +$2.56M +334,861 New
MCM
37
Moore Capital Management
New York
$2.38M +$2.38M +311,124 New
Adage Capital Partners
38
Adage Capital Partners
Massachusetts
$2.35M -$11.5M -1,500,000 -83%
Millennium Management
39
Millennium Management
New York
$2.3M -$4.08M -533,729 -64%
SC
40
SummitTX Capital
Texas
$2.21M +$1.38M +180,086 +166%
QOP
41
Quinn Opportunity Partners
Virginia
$2.2M -$804K -105,120 -27%
AQR Capital Management
42
AQR Capital Management
Connecticut
$1.95M +$1.95M +255,495 New
Bank of America
43
Bank of America
North Carolina
$1.94M +$291K +38,119 +18%
AG
44
Algert Global
California
$1.91M +$1.91M +249,740 New
OFM
45
Omega Fund Management
Massachusetts
$1.91M – – –
TD Asset Management
46
TD Asset Management
Ontario, Canada
$1.86M -$182K -23,870 -9%
Bank of New York Mellon
47
Bank of New York Mellon
New York
$1.57M -$33.9K -4,431 -2%
Wellington Management Group
48
Wellington Management Group
Massachusetts
$1.51M -$84.8K -11,091 -5%
NFT
49
Nan Fung Trinity
Hong Kong
$1.5M -$2.9M -379,200 -66%
Manulife (Manufacturers Life Insurance)
50
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.47M +$103K +13,439 +8%
1
2
3 4 5

REPL Hedge Fund Activity: Q1 2026 in Review

180 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Replimune Group (REPL) for Q1 2026, worth a combined $619M — down 20% from $775M a quarter earlier.

Buyers outnumbered sellers: 47 funds opened new REPL positions and 29 closed out — a net gain of 18 holders — while 61 added to existing stakes and 49 trimmed.

The largest buyer was Suvretta Capital Management, adding an estimated $32M. The largest seller was Commodore Capital, exiting entirely with an estimated $13.9M sold.

  • 180 institutional investors held Replimune Group (REPL) as of Q1 2026, up from 164 in Q4 2025.
  • Funds reported $619M of Replimune Group stock for Q1 2026, down 20% quarter-over-quarter.
  • 47 funds opened new Replimune Group positions in Q1 2026 and 29 closed out, a net change of +18 holders.
  • The largest Replimune Group buyer in Q1 2026 was Suvretta Capital Management, an estimated $32M added.
  • The largest Replimune Group seller in Q1 2026 was Commodore Capital, an estimated $13.9M sold.

Based on aggregated 13F filings for Q1 2026.