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Arcus Biosciences

209 hedge funds and large institutions have $2.89B invested in Arcus Biosciences in 2025 Q4 according to their latest regulatory filings, with 48 funds opening new positions, 95 increasing their positions, 38 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,666% more call options, than puts

Call options by funds: $92.8M | Put options by funds: $5.26M

150% more repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 38

112% more capital invested

Capital invested by funds: $1.37B → $2.89B (+$1.53B)

100% more funds holding in top 10

Funds holding in top 10: 24 (+2)

78% more first-time investments, than exits

New positions opened: 48 | Existing positions closed: 27

17.94% more ownership

Funds ownership: 94.53%112.48% (+18%)

10% more funds holding

Funds holding: 190209 (+19)

Holders
209
Holders Change
+19
Holders Change %
+10%
% of All Funds
2.54%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.05%
New
48
Increased
95
Reduced
38
Closed
27
Calls
$92.8M
Puts
$5.26M
Net Calls
+$87.6M
Net Calls Change
+$43.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Massachusetts Financial Services
126
Massachusetts Financial Services
Massachusetts
$553K -$15.7K -769 -3%
Ohio Public Employees Retirement System (OPERS)
127
Ohio Public Employees Retirement System (OPERS)
Ohio
$524K
YCM
128
Yousif Capital Management
Michigan
$509K +$34.2K +1,674 +8%
COPPSERS
129
Commonwealth of Pennsylvania Public School Employees Retirement System
Pennsylvania
$504K +$71.8K +3,517 +20%
Verition Fund Management
130
Verition Fund Management
Connecticut
$502K -$476K -23,316 -53%
PFSRSONJ
131
Police & Firemen's Retirement System of New Jersey
New Jersey
$502K +$46.1K +2,260 +12%
OPERF
132
Oregon Public Employees Retirement Fund
Oregon
$464K +$79.6K +3,900 +25%
Comerica Bank
133
Comerica Bank
Texas
$455K -$7.81K -383 -2%
Allspring Global Investments
134
Allspring Global Investments
North Carolina
$440K +$33.6K +1,649 +10%
KK
135
KLP Kapitalforvaltning
Norway
$434K -$75.5K -3,700 -17%
SO
136
STRS Ohio
Ohio
$400K +$343K +16,800 New
DekaBank Deutsche Girozentrale
137
DekaBank Deutsche Girozentrale
Germany
$396K
TRSOTSOK
138
Teachers Retirement System of the State of Kentucky
Kentucky
$380K
QCM
139
Quantinno Capital Management
New York
$380K +$15K +735 +5%
ProShare Advisors
140
ProShare Advisors
Maryland
$366K +$48.5K +2,377 +18%
State Board of Administration of Florida Retirement System
141
State Board of Administration of Florida Retirement System
Florida
$359K
VOYA Investment Management
142
VOYA Investment Management
Georgia
$319K -$350K -17,171 -56%
Teacher Retirement System of Texas
143
Teacher Retirement System of Texas
Texas
$301K -$84.2K -4,127 -25%
MSRPS
144
Maryland State Retirement & Pension System
Maryland
$295K +$253K +12,381 New
VIA
145
Virtus Investment Advisers
Connecticut
$294K +$3.81K +187 +2%
Victory Capital Management
146
Victory Capital Management
Texas
$293K +$32.8K +1,610 +15%
Rockefeller Capital Management
147
Rockefeller Capital Management
New York
$291K +$171K +8,368 +217%
Pictet Asset Management
148
Pictet Asset Management
Switzerland
$273K +$234K +11,462 New
SEI Investments
149
SEI Investments
Pennsylvania
$245K +$210K +10,295 New
MOACM
150
Mutual of America Capital Management
New York
$233K +$199K +9,758 New

RCUS Hedge Fund Activity: Q4 2025 in Review

209 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Arcus Biosciences (RCUS) for Q4 2025, worth a combined $2.89B — up 112% from $1.37B a quarter earlier.

Buyers outnumbered sellers: 48 funds opened new RCUS positions and 27 closed out — a net gain of 21 holders — while 95 added to existing stakes and 38 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $79.9M. The largest seller was Fidelity Investments, cutting an estimated $23.7M.

  • 209 institutional investors held Arcus Biosciences (RCUS) as of Q4 2025, up from 190 in Q3 2025.
  • Funds reported $2.89B of Arcus Biosciences stock for Q4 2025, up 112% quarter-over-quarter.
  • 48 funds opened new Arcus Biosciences positions in Q4 2025 and 27 closed out, a net change of +21 holders.
  • The largest Arcus Biosciences buyer in Q4 2025 was Wellington Management Group, an estimated $79.9M added.
  • The largest Arcus Biosciences seller in Q4 2025 was Fidelity Investments, an estimated $23.7M sold.

Based on aggregated 13F filings for Q4 2025.