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Arcus Biosciences

209 hedge funds and large institutions have $2.89B invested in Arcus Biosciences in 2025 Q4 according to their latest regulatory filings, with 48 funds opening new positions, 95 increasing their positions, 38 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,666% more call options, than puts

Call options by funds: $92.8M | Put options by funds: $5.26M

150% more repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 38

112% more capital invested

Capital invested by funds: $1.37B → $2.89B (+$1.53B)

100% more funds holding in top 10

Funds holding in top 10: 24 (+2)

78% more first-time investments, than exits

New positions opened: 48 | Existing positions closed: 27

17.94% more ownership

Funds ownership: 94.53%112.48% (+18%)

10% more funds holding

Funds holding: 190209 (+19)

Holders
209
Holders Change
+19
Holders Change %
+10%
% of All Funds
2.54%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.05%
New
48
Increased
95
Reduced
38
Closed
27
Calls
$92.8M
Puts
$5.26M
Net Calls
+$87.6M
Net Calls Change
+$43.6M
Name Holding Trade Value Shares
Change
Change in
Stake
California State Teachers Retirement System (CalSTRS)
76
California State Teachers Retirement System (CalSTRS)
California
$2.16M +$544K +26,664 +42%
PA
77
Parallel Advisors
California
$2.06M -$29.6K -1,450 -2%
AQR Capital Management
78
AQR Capital Management
Connecticut
$2.05M +$49.6K +2,430 +3%
D.E. Shaw & Co
79
D.E. Shaw & Co
New York
$2.04M +$1.34M +65,699 +331%
Thrivent Financial for Lutherans
80
Thrivent Financial for Lutherans
Minnesota
$1.92M +$622K +30,484 +61%
Prudential Financial
81
Prudential Financial
New Jersey
$1.89M +$188K +9,193 +13%
Canada Life
82
Canada Life
Manitoba, Canada
$1.76M +$298K +14,610 +25%
JP Morgan Chase
83
JP Morgan Chase
New York
$1.73M +$180K +8,813 +14%
Deutsche Bank
84
Deutsche Bank
Germany
$1.49M +$292K +14,316 +30%
WG
85
Winton Group
United Kingdom
$1.48M -$612K -29,978 -33%
DFCM
86
Dark Forest Capital Management
Puerto Rico
$1.44M -$1.62M -79,407 -57%
State of Wisconsin Investment Board
87
State of Wisconsin Investment Board
Wisconsin
$1.4M +$574K +28,117 +92%
T. Rowe Price Associates
88
T. Rowe Price Associates
Maryland
$1.4M +$190K +9,307 +19%
SAM
89
Sectoral Asset Management
Quebec, Canada
$1.36M -$6.35M -311,125 -85%
FBCM
90
Fort Baker Capital Management
California
$1.25M +$1.07M +52,523 New
BGM
91
Burkehill Global Management
New York
$1.19M +$1.02M +50,000 New
Jane Street
92
Jane Street
New York
$1.11M -$3.65M -179,127 -79%
SG Americas Securities
93
SG Americas Securities
New York
$1.08M +$259K +12,714 +39%
Corient Private Wealth
94
Corient Private Wealth
Florida
$1.08M +$468K +22,958 +104%
FAM
95
Fred Alger Management
New York
$1.07M +$913K +44,758 New
MIM
96
MetLife Investment Management
New Jersey
$1.04M +$40.2K +1,972 +5%
SOADOR
97
State of Alaska Department of Revenue
Alaska
$1.03M +$176K +8,642 +25%
New York State Common Retirement Fund
98
New York State Common Retirement Fund
New York
$1.02M +$431K +21,148 +97%
Janus Henderson Group
99
Janus Henderson Group
United Kingdom
$1.01M +$231K +11,300 +36%
Manulife (Manufacturers Life Insurance)
100
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1M +$142K +6,963 +20%

RCUS Hedge Fund Activity: Q4 2025 in Review

209 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Arcus Biosciences (RCUS) for Q4 2025, worth a combined $2.89B — up 112% from $1.37B a quarter earlier.

Buyers outnumbered sellers: 48 funds opened new RCUS positions and 27 closed out — a net gain of 21 holders — while 95 added to existing stakes and 38 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $79.9M. The largest seller was Fidelity Investments, cutting an estimated $23.7M.

  • 209 institutional investors held Arcus Biosciences (RCUS) as of Q4 2025, up from 190 in Q3 2025.
  • Funds reported $2.89B of Arcus Biosciences stock for Q4 2025, up 112% quarter-over-quarter.
  • 48 funds opened new Arcus Biosciences positions in Q4 2025 and 27 closed out, a net change of +21 holders.
  • The largest Arcus Biosciences buyer in Q4 2025 was Wellington Management Group, an estimated $79.9M added.
  • The largest Arcus Biosciences seller in Q4 2025 was Fidelity Investments, an estimated $23.7M sold.

Based on aggregated 13F filings for Q4 2025.