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Arcus Biosciences

209 hedge funds and large institutions have $2.89B invested in Arcus Biosciences in 2025 Q4 according to their latest regulatory filings, with 48 funds opening new positions, 95 increasing their positions, 38 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,666% more call options, than puts

Call options by funds: $92.8M | Put options by funds: $5.26M

150% more repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 38

112% more capital invested

Capital invested by funds: $1.37B → $2.89B (+$1.53B)

100% more funds holding in top 10

Funds holding in top 10: 24 (+2)

78% more first-time investments, than exits

New positions opened: 48 | Existing positions closed: 27

17.94% more ownership

Funds ownership: 94.53%112.48% (+18%)

10% more funds holding

Funds holding: 190209 (+19)

Holders
209
Holders Change
+19
Holders Change %
+10%
% of All Funds
2.54%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.05%
New
48
Increased
95
Reduced
38
Closed
27
Calls
$92.8M
Puts
$5.26M
Net Calls
+$87.6M
Net Calls Change
+$43.6M
Name Holding Trade Value Shares
Change
Change in
Stake
Ameriprise
51
Ameriprise
Minnesota
$5.38M +$328K +16,056 +8%
Tudor Investment Corp
52
Tudor Investment Corp
Connecticut
$4.97M +$4.26M +208,639 New
Legal & General Group
53
Legal & General Group
United Kingdom
$4.89M +$547K +26,806 +15%
NIP
54
Nicholas Investment Partners
California
$4.87M +$4.17M +204,338 New
Connor, Clark & Lunn Investment Management (CC&L)
55
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$4.84M +$2.39M +117,210 +136%
RSCM
56
Rock Springs Capital Management
Maryland
$4.29M +$3.67M +180,000 New
PSC
57
Patient Square Capital
California
$4.05M +$3.47M +170,000 New
GIM
58
Granahan Investment Management
Massachusetts
$4.05M -$5.83M -285,656 -63%
Millennium Management
59
Millennium Management
New York
$4.02M -$9.51M -466,068 -73%
Swiss National Bank
60
Swiss National Bank
Switzerland
$4M +$704K +34,500 +26%
UBS AM
61
UBS AM
Illinois
$3.43M +$1.15M +56,322 +64%
Alyeska Investment Group
62
Alyeska Investment Group
Illinois
$3.4M +$2.91M +142,518 New
N
63
Nuveen
North Carolina
$3.37M +$301K +14,762 +12%
Two Sigma Investments
64
Two Sigma Investments
New York
$3.33M -$6.77M -331,891 -70%
Russell Investments Group
65
Russell Investments Group
United Kingdom
$3.24M +$1.1M +53,892 +66%
PIM
66
Platinum Investment Management
Australia
$3.2M -$399K -19,566 -13%
AllianceBernstein
67
AllianceBernstein
Tennessee
$3.17M -$83.5K -4,091 -3%
American Century Companies
68
American Century Companies
Missouri
$3.07M +$68.9K +3,378 +3%
DMKJ
69
David M. Knott Jr
$2.89M +$531K +26,041 +27%
Citadel Advisors
70
Citadel Advisors
Florida
$2.5M -$3.88M -190,353 -65%
LP
71
LMR Partners
United Kingdom
$2.38M +$2.04M +100,000 New
Wells Fargo
72
Wells Fargo
California
$2.37M +$633K +31,002 +45%
SSA
73
Schonfeld Strategic Advisors
New York
$2.32M +$987K +48,389 +99%
Rafferty Asset Management
74
Rafferty Asset Management
New York
$2.21M +$475K +23,280 +33%
New York State Teachers Retirement System (NYSTRS)
75
New York State Teachers Retirement System (NYSTRS)
New York
$2.2M +$20.4K +1,000 +1%

RCUS Hedge Fund Activity: Q4 2025 in Review

209 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Arcus Biosciences (RCUS) for Q4 2025, worth a combined $2.89B — up 112% from $1.37B a quarter earlier.

Buyers outnumbered sellers: 48 funds opened new RCUS positions and 27 closed out — a net gain of 21 holders — while 95 added to existing stakes and 38 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $79.9M. The largest seller was Fidelity Investments, cutting an estimated $23.7M.

  • 209 institutional investors held Arcus Biosciences (RCUS) as of Q4 2025, up from 190 in Q3 2025.
  • Funds reported $2.89B of Arcus Biosciences stock for Q4 2025, up 112% quarter-over-quarter.
  • 48 funds opened new Arcus Biosciences positions in Q4 2025 and 27 closed out, a net change of +21 holders.
  • The largest Arcus Biosciences buyer in Q4 2025 was Wellington Management Group, an estimated $79.9M added.
  • The largest Arcus Biosciences seller in Q4 2025 was Fidelity Investments, an estimated $23.7M sold.

Based on aggregated 13F filings for Q4 2025.