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Arcus Biosciences

209 hedge funds and large institutions have $2.89B invested in Arcus Biosciences in 2025 Q4 according to their latest regulatory filings, with 48 funds opening new positions, 95 increasing their positions, 38 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,666% more call options, than puts

Call options by funds: $92.8M | Put options by funds: $5.26M

150% more repeat investments, than reductions

Existing positions increased: 95 | Existing positions reduced: 38

112% more capital invested

Capital invested by funds: $1.37B → $2.89B (+$1.53B)

100% more funds holding in top 10

Funds holding in top 10: 24 (+2)

78% more first-time investments, than exits

New positions opened: 48 | Existing positions closed: 27

17.94% more ownership

Funds ownership: 94.53%112.48% (+18%)

10% more funds holding

Funds holding: 190209 (+19)

Holders
209
Holders Change
+19
Holders Change %
+10%
% of All Funds
2.54%
Holding in Top 10
4
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+100%
% of All Funds
0.05%
New
48
Increased
95
Reduced
38
Closed
27
Calls
$92.8M
Puts
$5.26M
Net Calls
+$87.6M
Net Calls Change
+$43.6M
Name Holding Trade Value Shares
Change
Change in
Stake
TECP
26
Trails Edge Capital Partners
Georgia
$21.8M +$18.7M +916,313 New
Franklin Resources
27
Franklin Resources
California
$20.3M +$17.4M +853,491 New
Balyasny Asset Management
28
Balyasny Asset Management
Illinois
$19.4M +$14.6M +715,188 +713%
Northern Trust
29
Northern Trust
Illinois
$18.9M +$1.78M +87,002 +12%
CS
30
Candriam SCA
Luxembourg
$18.8M +$8.41M +412,172 +109%
CM
31
Caption Management
Oklahoma
$18.3M +$15.7M +767,698 New
SCM
32
Soleus Capital Management
Connecticut
$17M +$14.5M +711,983 New
FTM
33
First Turn Management
California
$13.5M +$11.5M +565,142 New
DC
34
Decheng Capital
California
$12.9M -$123K -6,050 -1%
Bank of New York Mellon
35
Bank of New York Mellon
New York
$12M +$699K +34,252 +7%
DCM
36
DAFNA Capital Management
California
$10.3M -$4M -196,297 -31%
BNP Paribas Financial Markets
37
BNP Paribas Financial Markets
France
$10.1M +$6.94M +340,048 +405%
Invesco
38
Invesco
Georgia
$9.87M +$2.49M +121,961 +42%
UBS Group
39
UBS Group
Switzerland
$9.8M +$4.98M +243,855 +146%
Principal Financial Group
40
Principal Financial Group
Iowa
$9.71M +$1.49M +72,989 +22%
PP
41
PDT Partners
New York
$9.25M
Aberdeen Group
42
Aberdeen Group
United Kingdom
$9.17M +$1.08M +52,930 +16%
NAMI
43
Nomura Asset Management International
Pennsylvania
$9.03M +$7.73M +379,100 New
Susquehanna International Group
44
Susquehanna International Group
Pennsylvania
$8.15M -$965K -47,276 -12%
AAA
45
Affinity Asset Advisors
New York
$7.15M +$6.12M +300,000 New
Public Sector Pension Investment Board (PSP Investments)
46
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$7.04M +$522K +25,563 +9%
BBA
47
Baker Bros. Advisors
New York
$6.43M +$5.51M +270,000 New
Hudson Bay Capital Management
48
Hudson Bay Capital Management
Connecticut
$5.72M -$2.04M -100,000 -29%
SPS
49
Susquehanna Portfolio Strategies
Pennsylvania
$5.72M
RhumbLine Advisers
50
RhumbLine Advisers
Massachusetts
$5.41M +$357K +17,510 +8%

RCUS Hedge Fund Activity: Q4 2025 in Review

209 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Arcus Biosciences (RCUS) for Q4 2025, worth a combined $2.89B — up 112% from $1.37B a quarter earlier.

Buyers outnumbered sellers: 48 funds opened new RCUS positions and 27 closed out — a net gain of 21 holders — while 95 added to existing stakes and 38 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $79.9M. The largest seller was Fidelity Investments, cutting an estimated $23.7M.

  • 209 institutional investors held Arcus Biosciences (RCUS) as of Q4 2025, up from 190 in Q3 2025.
  • Funds reported $2.89B of Arcus Biosciences stock for Q4 2025, up 112% quarter-over-quarter.
  • 48 funds opened new Arcus Biosciences positions in Q4 2025 and 27 closed out, a net change of +21 holders.
  • The largest Arcus Biosciences buyer in Q4 2025 was Wellington Management Group, an estimated $79.9M added.
  • The largest Arcus Biosciences seller in Q4 2025 was Fidelity Investments, an estimated $23.7M sold.

Based on aggregated 13F filings for Q4 2025.