|
1
|
NEA Management Company
Timonium,
Maryland
|
$51M
|
–
|
–
|
–
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$33.5M
|
+$2.84M
|
+187,977
|
+9%
|
|
|
3
|
Novo Holdings A/S
Hellerup,
Denmark
|
$29.7M
|
–
|
–
|
–
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$19.7M
|
–
|
–
|
–
|
|
|
5
|
VHCP Management II
New York
|
$11.2M
|
–
|
–
|
–
|
|
|
6
|
|
$9.4M
|
+$345K
|
+22,799
|
+4%
|
|
|
7
|
Millennium Management
New York
|
$9.22M
|
+$6.56M
|
+434,042
|
+220%
|
|
|
8
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$8.76M
|
–
|
–
|
–
|
|
|
9
|
Tekla Capital Management
Boston,
Massachusetts
|
$5.78M
|
–
|
–
|
–
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$5.21M
|
+$150K
|
+9,911
|
+3%
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$4.66M
|
+$4.83M
|
+319,414
|
New
|
|
|
12
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$4.06M
|
+$1.5M
|
+99,332
|
+56%
|
|
|
13
|
|
$3.74M
|
+$853K
|
+56,400
|
+28%
|
|
|
14
|
Ghost Tree Capital
New York
|
$3.43M
|
+$2.27M
|
+150,000
|
+176%
|
|
|
15
|
Baker Bros. Advisors
New York
|
$2.6M
|
–
|
–
|
–
|
|
|
16
|
Polar Capital
London,
United Kingdom
|
$2.56M
|
+$1.51M
|
+100,000
|
+133%
|
|
|
17
|
State Street
Boston,
Massachusetts
|
$2.27M
|
+$67.4K
|
+4,459
|
+3%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$1.99M
|
+$96.5K
|
+6,382
|
+5%
|
|
|
19
|
Ameriprise
Minneapolis,
Minnesota
|
$1.78M
|
-$44K
|
-2,909
|
-2%
|
|
|
20
|
Rhenman & Partners Asset Management
Stockholm,
Sweden
|
$1.75M
|
+$1.81M
|
+119,697
|
New
|
|
|
21
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$1.69M
|
+$529K
|
+35,000
|
+43%
|
|
|
22
|
Emory University
Atlanta,
Georgia
|
$1.64M
|
+$740K
|
+48,940
|
+78%
|
|
|
23
|
Deerfield Management
New York
|
$1.49M
|
+$296K
|
+19,557
|
+24%
|
|
|
24
|
Eventide Asset Management
Boston,
Massachusetts
|
$1.46M
|
–
|
–
|
–
|
|
|
25
|
Geode Capital Management
Boston,
Massachusetts
|
$1.12M
|
+$24.9K
|
+1,647
|
+2%
|
|
