|
1
|
NEA Management Company
Timonium,
Maryland
|
$65.5M
|
–
|
–
|
–
|
|
|
2
|
Wellington Management Group
Boston,
Massachusetts
|
$39.4M
|
+$10.7M
|
+473,635
|
+29%
|
|
|
3
|
Novo Holdings A/S
Hellerup,
Denmark
|
$38.1M
|
–
|
–
|
–
|
|
|
4
|
RA Capital Management
Boston,
Massachusetts
|
$25.3M
|
–
|
–
|
–
|
|
|
5
|
VHCP Management II
New York
|
$14.4M
|
+$1.01M
|
+44,742
|
+6%
|
|
|
6
|
|
$11.6M
|
+$6.23M
|
+276,288
|
+80%
|
|
|
7
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$11.2M
|
-$4.26M
|
-188,959
|
-24%
|
|
|
8
|
Tekla Capital Management
Boston,
Massachusetts
|
$7.42M
|
+$8.93M
|
+395,818
|
New
|
|
|
9
|
Acuta Capital Partners
Redwood City,
California
|
$7M
|
+$2.83M
|
+125,551
|
+51%
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$6.5M
|
+$1.72M
|
+76,349
|
+28%
|
|
|
11
|
|
$3.75M
|
+$1.14M
|
+50,432
|
+34%
|
|
|
12
|
Millennium Management
New York
|
$3.71M
|
+$3.42M
|
+151,737
|
+330%
|
|
|
13
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$3.35M
|
-$1.05M
|
-46,590
|
-21%
|
|
|
14
|
Baker Bros. Advisors
New York
|
$3.33M
|
–
|
–
|
–
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$2.83M
|
+$979K
|
+43,376
|
+40%
|
|
|
16
|
Numeric Investors
Boston,
Massachusetts
|
$2.48M
|
+$2.99M
|
+132,558
|
New
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$2.44M
|
+$1.21M
|
+53,730
|
+70%
|
|
|
18
|
Ameriprise
Minneapolis,
Minnesota
|
$2.34M
|
-$392K
|
-17,369
|
-12%
|
|
|
19
|
Adage Capital Partners
Boston,
Massachusetts
|
$2.15M
|
-$587K
|
-26,000
|
-18%
|
|
|
20
|
Fidelity International
Hamilton,
Bermuda
|
$1.96M
|
–
|
–
|
–
|
|
|
21
|
Nexthera Capital
New York
|
$1.91M
|
+$2.3M
|
+102,054
|
New
|
|
|
22
|
Eventide Asset Management
Boston,
Massachusetts
|
$1.87M
|
+$2.26M
|
+100,000
|
New
|
|
|
23
|
Ghost Tree Capital
New York
|
$1.59M
|
-$4.85M
|
-215,000
|
-72%
|
|
|
24
|
Deerfield Management
New York
|
$1.55M
|
-$2.15M
|
-95,237
|
-54%
|
|
|
25
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$1.52M
|
+$1.83M
|
+81,000
|
New
|
|
