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Ultragenyx Pharmaceutical

282 hedge funds and large institutions have $2.16B invested in Ultragenyx Pharmaceutical in 2025 Q4 according to their latest regulatory filings, with 54 funds opening new positions, 110 increasing their positions, 90 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less ownership

Funds ownership:

less funds holding

Funds holding:

17% less first-time investments, than exits

New positions opened: 54 | Existing positions closed: 65

25% less capital invested

Capital invested by funds: $2.87B → $2.16B (-$715M)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

Holders
282
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$75.9M
Puts
$47.6M
Net Calls
Net Calls Change

Top Buyers

1 +$65.6M
2 +$30.1M
3 +$29.5M
4
Millennium Management
Millennium Management
New York
+$25.7M
5
Jane Street
Jane Street
New York
+$21.9M

Top Sellers

1 -$152M
2 -$31.1M
3 -$29.6M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$24.9M
5
VPC
Vestal Point Capital
New York
-$22.6M
Name Holding Trade Value Shares
Change
Change in
Stake
X
176
Xponance
Pennsylvania
$331K
STA
177
Summit Trail Advisors
New York
$330K
Universal-Beteiligungs- und Servicegesellschaft
178
Universal-Beteiligungs- und Servicegesellschaft
Germany
$323K
Mercer Global Advisors
179
Mercer Global Advisors
Colorado
$321K
VCM
180
Voleon Capital Management
California
$321K
Tudor Investment Corp
181
Tudor Investment Corp
Connecticut
$309K
ORI
182
Oak Ridge Investments
Illinois
$308K
Walleye Trading
183
Walleye Trading
New York
$303K
Carson Wealth (CWM LLC)
184
Carson Wealth (CWM LLC)
Nebraska
$302K
EAM
185
Erste Asset Management
Austria
$296K
BMSSC
186
B. Metzler seel. Sohn & Co
Germany
$296K
IC
187
Ikarian Capital
Texas
$291K
SOAM
188
SBI Okasan Asset Management
Japan
$284K
BAM
189
Blueshift Asset Management
New Jersey
$284K
Wealth Enhancement Advisory Services
190
Wealth Enhancement Advisory Services
Minnesota
$264K
CAPTRUST Financial Advisors
191
CAPTRUST Financial Advisors
North Carolina
$262K
Creative Planning
192
Creative Planning
Kansas
$259K
PAP
193
Persistent Asset Partners
Hong Kong
$254K
Canada Life
194
Canada Life
Manitoba, Canada
$245K
Mariner
195
Mariner
Kansas
$236K
PFCS
196
Pale Fire Capital SE
Czech Republic
$235K
MG
197
Marex Group
$222K
CB
198
Commerce Bank
Missouri
$209K
DFCM
199
Dark Forest Capital Management
Puerto Rico
$209K
Public Employees Retirement Association of Colorado
200
Public Employees Retirement Association of Colorado
Colorado
$206K