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Ultragenyx Pharmaceutical

282 hedge funds and large institutions have $2.16B invested in Ultragenyx Pharmaceutical in 2025 Q4 according to their latest regulatory filings, with 54 funds opening new positions, 110 increasing their positions, 90 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less ownership

Funds ownership:

less funds holding

Funds holding:

17% less first-time investments, than exits

New positions opened: 54 | Existing positions closed: 65

25% less capital invested

Capital invested by funds: $2.87B → $2.16B (-$715M)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

Holders
282
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$75.9M
Puts
$47.6M
Net Calls
Net Calls Change

Top Buyers

1 +$65.6M
2 +$30.1M
3 +$29.5M
4
Millennium Management
Millennium Management
New York
+$25.7M
5
Jane Street
Jane Street
New York
+$21.9M

Top Sellers

1 -$152M
2 -$31.1M
3 -$29.6M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$24.9M
5
VPC
Vestal Point Capital
New York
-$22.6M
Name Holding Trade Value Shares
Change
Change in
Stake
BC
126
Birchview Capital
Vermont
$1.43M
FISPB
127
Fideuram - Intesa Sanpaolo Private Banking
$1.41M
ET
128
Entropy Technologies
New York
$1.39M
State of Wisconsin Investment Board
129
State of Wisconsin Investment Board
Wisconsin
$1.35M
Nordea Investment Management
130
Nordea Investment Management
Sweden
$1.32M
PA
131
Profund Advisors
Maryland
$1.3M
II
132
Ishara Investments
California
$1.15M
QCM
133
Quantinno Capital Management
New York
$1.14M
GC
134
Guggenheim Capital
Illinois
$1.13M
SRL
135
Scientech Research LLC
New Jersey
$1.1M
WCM
136
Wedge Capital Management
North Carolina
$973K
PFSRSONJ
137
Police & Firemen's Retirement System of New Jersey
New Jersey
$906K
Treasurer of the State of North Carolina
138
Treasurer of the State of North Carolina
North Carolina
$888K
AIMCA
139
Alberta Investment Management Corp (AIMCo)
Alberta, Canada
$883K
Janus Henderson Group
140
Janus Henderson Group
United Kingdom
$840K
Walleye Capital
141
Walleye Capital
New York
$839K
Pathstone Holdings
142
Pathstone Holdings
New Jersey
$790K
New York State Common Retirement Fund
143
New York State Common Retirement Fund
New York
$783K
Handelsbanken Fonder
144
Handelsbanken Fonder
Sweden
$771K
SG Americas Securities
145
SG Americas Securities
New York
$741K
SCM
146
Superstring Capital Management
New York
$730K
Toronto Dominion Bank
147
Toronto Dominion Bank
Ontario, Canada
$729K
State of New Jersey Common Pension Fund D
148
State of New Jersey Common Pension Fund D
New Jersey
$681K
Zurich Cantonal Bank
149
Zurich Cantonal Bank
Switzerland
$650K
HT
150
Headlands Technologies
Illinois
$649K