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Ultragenyx Pharmaceutical

282 hedge funds and large institutions have $2.16B invested in Ultragenyx Pharmaceutical in 2025 Q4 according to their latest regulatory filings, with 54 funds opening new positions, 110 increasing their positions, 90 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less ownership

Funds ownership:

less funds holding

Funds holding:

17% less first-time investments, than exits

New positions opened: 54 | Existing positions closed: 65

25% less capital invested

Capital invested by funds: $2.87B → $2.16B (-$715M)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

Holders
282
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
3
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$75.9M
Puts
$47.6M
Net Calls
Net Calls Change

Top Buyers

1 +$65.6M
2 +$30.1M
3 +$29.5M
4
Millennium Management
Millennium Management
New York
+$25.7M
5
Jane Street
Jane Street
New York
+$21.9M

Top Sellers

1 -$152M
2 -$31.1M
3 -$29.6M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$24.9M
5
VPC
Vestal Point Capital
New York
-$22.6M
Name Holding Trade Value Shares
Change
Change in
Stake
PA
101
Pinnacle Associates
New York
$2.57M
BHCM
102
Brevan Howard Capital Management
Jersey
$2.42M
RhumbLine Advisers
103
RhumbLine Advisers
Massachusetts
$2.34M
TC
104
TwinBeech Capital
New York
$2.3M
CAG
105
Crestwood Advisors Group
Massachusetts
$2.3M
EP
106
Edgestream Partners
New Jersey
$2.3M
WorldQuant Millennium Advisors
107
WorldQuant Millennium Advisors
New York
$2.23M
State Board of Administration of Florida Retirement System
108
State Board of Administration of Florida Retirement System
Florida
$2.23M
ACM
109
Aquatic Capital Management
Illinois
$2.01M
California State Teachers Retirement System (CalSTRS)
110
California State Teachers Retirement System (CalSTRS)
California
$1.92M
SI
111
Sofinnova Investments
California
$1.92M
TD Asset Management
112
TD Asset Management
Ontario, Canada
$1.89M
Man Group
113
Man Group
United Kingdom
$1.8M
EGM
114
Engineers Gate Manager
New York
$1.76M
AAA
115
Affinity Asset Advisors
New York
$1.73M
FMI
116
F/M Investments
District of Columbia
$1.69M
MFAM
117
Motley Fool Asset Management
Virginia
$1.67M
Marshall Wace
118
Marshall Wace
United Kingdom
$1.66M
Citigroup
119
Citigroup
New York
$1.6M
DZ Bank
120
DZ Bank
Germany
$1.55M
Mirae Asset Global ETFs Holdings
121
Mirae Asset Global ETFs Holdings
Hong Kong
$1.52M
QC
122
Quadrature Capital
United Kingdom
$1.52M
Wells Fargo
123
Wells Fargo
California
$1.46M
HWAM
124
Hennion & Walsh Asset Management
New Jersey
$1.43M
PHP
125
Parkman Healthcare Partners
Connecticut
$1.43M