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Ultragenyx Pharmaceutical

287 hedge funds and large institutions have $2.16B invested in Ultragenyx Pharmaceutical in 2025 Q4 according to their latest regulatory filings, with 57 funds opening new positions, 111 increasing their positions, 91 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

60% more call options, than puts

Call options by funds: $75.9M | Put options by funds: $47.6M

22% more repeat investments, than reductions

Existing positions increased: 111 | Existing positions reduced: 91

1.7% less ownership

Funds ownership: 99.08%97.37% (-1.7%)

5% less funds holding

Funds holding: 302287 (-15)

12% less first-time investments, than exits

New positions opened: 57 | Existing positions closed: 65

25% less capital invested

Capital invested by funds: $2.87B → $2.16B (-$710M)

50% less funds holding in top 10

Funds holding in top 10: 42 (-2)

Holders
287
Holders Change
-15
Holders Change %
-4.97%
% of All Funds
3.49%
Holding in Top 10
2
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
57
Increased
111
Reduced
91
Closed
65
Calls
$75.9M
Puts
$47.6M
Net Calls
+$28.3M
Net Calls Change
-$25.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Teacher Retirement System of Texas
51
Teacher Retirement System of Texas
Texas
$8.01M +$10.8M +327,502 +1,571%
D.E. Shaw & Co
52
D.E. Shaw & Co
New York
$7.93M +$3.52M +107,123 +45%
Manulife (Manufacturers Life Insurance)
53
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$7.61M -$452K -13,754 -4%
GGI
54
GordonMD Global Investments
California
$7.57M +$10.8M +329,101 New
EP
55
Eversept Partners
New York
$7.3M +$10.4M +317,182 New
Massachusetts Financial Services
56
Massachusetts Financial Services
Massachusetts
$7.13M -$6.28M -191,055 -38%
Franklin Resources
57
Franklin Resources
California
$7.11M -$12.1M -368,122 -54%
SFM
58
Sphera Funds Management
Israel
$6.91M -$1.71M -51,935 -15%
GPP
59
Great Point Partners
Connecticut
$6.9M +$9.87M +300,000 New
Bank of New York Mellon
60
Bank of New York Mellon
New York
$6.87M -$860K -26,139 -8%
MFWM
61
Motley Fool Wealth Management
Virginia
$6.84M -$1.91M -58,054 -16%
NM
62
Newtyn Management
New York
$6.81M +$9.73M +295,915 New
Verition Fund Management
63
Verition Fund Management
Connecticut
$6.49M +$8.51M +258,856 +1,101%
Adage Capital Partners
64
Adage Capital Partners
Massachusetts
$6.44M -$4.93M -150,000 -35%
Ameriprise
65
Ameriprise
Minnesota
$6.37M +$4.55M +138,243 +100%
Connor, Clark & Lunn Investment Management (CC&L)
66
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$6.07M +$6.08M +184,947 +234%
Ensign Peak Advisors
67
Ensign Peak Advisors
Utah
$5.76M +$2.41M +73,150 +41%
Invesco
68
Invesco
Georgia
$5.3M -$18.6M -564,578 -71%
6CM
69
683 Capital Management
New York
$5.12M +$3.83M +116,395 +110%
CM
70
Caption Management
Oklahoma
$5.05M +$1.81M +54,999 +33%
AG
71
Algert Global
California
$5.04M -$3.37M -102,401 -32%
BOCH
72
Blue Owl Capital Holdings
New York
$4.89M -$6.9M -209,800 -50%
EA
73
Emerald Advisers
Pennsylvania
$4.88M -$6.78M -206,208 -49%
Los Angeles Capital Management
74
Los Angeles Capital Management
California
$4.73M -$1.99M -60,515 -31%
UBS AM
75
UBS AM
Illinois
$4.69M -$96.5K -2,935 -1%