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Ultragenyx Pharmaceutical

299 hedge funds and large institutions have $3.25B invested in Ultragenyx Pharmaceutical in 2025 Q1 according to their latest regulatory filings, with 33 funds opening new positions, 127 increasing their positions, 104 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

40% more funds holding in top 10

Funds holding in top 10: 57 (+2)

22% more repeat investments, than reductions

Existing positions increased: 127 | Existing positions reduced: 104

2.35% more ownership

Funds ownership: 94.76%97.11% (+2.4%)

4% more call options, than puts

Call options by funds: $43.9M | Put options by funds: $42.2M

4% less funds holding

Funds holding: 312299 (-13)

12% less capital invested

Capital invested by funds: $3.68B → $3.25B (-$427M)

25% less first-time investments, than exits

New positions opened: 33 | Existing positions closed: 44

Holders
299
Holders Change
-13
Holders Change %
-4.17%
% of All Funds
4.01%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.09%
New
33
Increased
127
Reduced
104
Closed
44
Calls
$43.9M
Puts
$42.2M
Net Calls
+$1.65M
Net Calls Change
+$8.06M
Name Holding Trade Value Shares
Change
Change in
Stake
Aberdeen Group
51
Aberdeen Group
United Kingdom
$17.3M +$6.73M +161,779 +51%
UBS Group
52
UBS Group
Switzerland
$17M +$5.98M +143,831 +44%
Axa
53
Axa
France
$16.5M -$12.2K -293 -0.1%
Man Group
54
Man Group
United Kingdom
$16.5M +$6.56M +157,754 +53%
MB
55
MPM BioImpact
Massachusetts
$14.4M +$309K +7,427 +2%
Fidelity Investments
56
Fidelity Investments
Massachusetts
$13.8M -$606K -14,562 -4%
Hudson Bay Capital Management
57
Hudson Bay Capital Management
Connecticut
$13.8M +$112K +2,700 +0.7%
CCM
58
Cutter Capital Management
New York
$13.7M -$1.14M -27,500 -7%
EMFAT
59
Emerald Mutual Fund Advisers Trust
Pennsylvania
$12.3M +$688K +16,538 +5%
Marshall Wace
60
Marshall Wace
United Kingdom
$12.1M -$29.8M -717,495 -68%
APM
61
Avidity Partners Management
Texas
$11.7M -$1.24M -29,900 -8%
DZ Bank
62
DZ Bank
Germany
$11.3M -$1.48M -35,496 -10%
JP Morgan Chase
63
JP Morgan Chase
New York
$11.2M +$4.31M +103,684 +50%
PHP
64
Parkman Healthcare Partners
Connecticut
$11M +$8.49M +204,085 +204%
Renaissance Technologies
65
Renaissance Technologies
New York
$10.8M +$1.87M +44,900 +18%
Manulife (Manufacturers Life Insurance)
66
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$10.6M +$3.19M +76,787 +35%
Macquarie Group
67
Macquarie Group
Australia
$10.3M +$24.4K +586 +0.2%
Schroder Investment Management Group
68
Schroder Investment Management Group
United Kingdom
$10M -$4.65M -111,876 -30%
TI
69
Trexquant Investment
Connecticut
$9.73M +$4.66M +112,010 +72%
WP
70
Woodline Partners
California
$9.72M -$45.5K -1,094 -0.4%
SFM
71
Sphera Funds Management
Israel
$9.68M +$1.61M +38,609 +17%
Legal & General Group
72
Legal & General Group
United Kingdom
$9.38M +$6.67M +160,235 +162%
Citadel Advisors
73
Citadel Advisors
Florida
$9.29M -$1.23M -29,630 -10%
PFM
74
Privium Fund Management
Netherlands
$9.05M -$357K -8,576 -3%
MCM
75
Moore Capital Management
New York
$8.69M -$208K -5,000 -2%

RARE Hedge Fund Activity: Q1 2025 in Review

299 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Ultragenyx Pharmaceutical (RARE) for Q1 2025, worth a combined $3.25B — down 12% from $3.68B a quarter earlier.

Sellers outnumbered buyers: 44 funds closed out of RARE and 33 opened new positions — a net loss of 11 holders — while 104 trimmed existing stakes and 127 added.

The largest buyer was Adage Capital Partners, adding an estimated $40.2M. The largest seller was Vestal Point Capital, cutting an estimated $41.6M.

  • 299 institutional investors held Ultragenyx Pharmaceutical (RARE) as of Q1 2025, down from 312 in Q4 2024.
  • Funds reported $3.25B of Ultragenyx Pharmaceutical stock for Q1 2025, down 12% quarter-over-quarter.
  • 33 funds opened new Ultragenyx Pharmaceutical positions in Q1 2025 and 44 closed out, a net change of -11 holders.
  • The largest Ultragenyx Pharmaceutical buyer in Q1 2025 was Adage Capital Partners, an estimated $40.2M added.
  • The largest Ultragenyx Pharmaceutical seller in Q1 2025 was Vestal Point Capital, an estimated $41.6M sold.

Based on aggregated 13F filings for Q1 2025.