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Ultragenyx Pharmaceutical
RARE

295 hedge funds and large institutions have $2.05B invested in Ultragenyx Pharmaceutical in 2026 Q1 according to their latest regulatory filings, with 62 funds opening new positions, 125 increasing their positions, 83 reducing their positions, and 48 closing their positions.

New
Increased
Maintained
Reduced
Closed

200% more funds holding in top 10

Funds holding in top 10: 2 → 6 (+4)

51% more repeat investments, than reductions

Existing positions increased: 125 | Existing positions reduced: 83

29% more first-time investments, than exits

New positions opened: 62 | Existing positions closed: 48

4.16% more ownership

Funds ownership: 97.37% → 101.53% (+4.2%)

3% more funds holding

Funds holding: 287 → 295 (+8)

8% more call options, than puts

Call options by funds: $27.9M | Put options by funds: $25.8M

5% less capital invested

Capital invested by funds: $2.16B → $2.05B (-$108M)

Holders
295
Holders Change
+8
Holders Change %
+2.79%
% of All Funds
3.63%
Holding in Top 10
6
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+200%
% of All Funds
0.07%
New
62
Increased
125
Reduced
83
Closed
48
Calls
$27.9M
Puts
$25.8M
Net Calls
+$2.02M
Net Calls Change
-$26.3M

Top Buyers

1
AQR Capital Management
AQR Capital Management
Connecticut
+$72.5M
2
SI
Sofinnova Investments
California
+$69M
3
BG
Bellevue Group
Switzerland
+$53.5M
4
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
+$46.3M
5
Two Sigma Investments
Two Sigma Investments
New York
+$40.1M

Top Sellers

1
JP Morgan Chase
JP Morgan Chase
New York
-$84M
2
BBA
Baker Bros. Advisors
New York
-$63.8M
3
Fidelity Investments
Fidelity Investments
Massachusetts
-$53.6M
4
SCM
Suvretta Capital Management
New York
-$46.4M
5
BNP Paribas Asset Management
BNP Paribas Asset Management
France
-$33.4M
Name Holding Trade Value Shares
Change 		Change in
Stake
Qube Research & Technologies (QRT)
26
Qube Research & Technologies (QRT)
United Kingdom
$19.2M +$20.6M +914,760 New
Point72 Asset Management
27
Point72 Asset Management
Connecticut
$18.7M +$20.1M +893,295 New
EHI
28
Eagle Health Investments
Connecticut
$18.5M +$19.9M +884,121 New
CCM
29
Catalio Capital Management
New York
$17.8M +$15.5M +688,247 +423%
UBS Group
30
UBS Group
Switzerland
$17.4M +$3.69M +163,929 +25%
SFM
31
Sphera Funds Management
Israel
$17M +$11.5M +508,710 +169%
T. Rowe Price Associates
32
T. Rowe Price Associates
Maryland
$16.8M -$16.9M -750,257 -48%
N
33
Nuveen
North Carolina
$13.9M -$3.14M -139,419 -17%
HF
34
HRT Financial
New York
$12.8M +$2.51M +111,550 +22%
VFT
35
Vanguard Fiduciary Trust
Pennsylvania
$12.7M +$13.7M +608,219 New
PAI
36
Palo Alto Investors
California
$12.5M +$3.04M +135,201 +29%
Legal & General Group
37
Legal & General Group
United Kingdom
$12.4M +$4.03M +179,021 +44%
Renaissance Technologies
38
Renaissance Technologies
New York
$11.8M +$4.4M +195,600 +53%
Charles Schwab
39
Charles Schwab
California
$11.7M -$911K -40,438 -7%
Pictet Asset Management
40
Pictet Asset Management
Switzerland
$11.7M -$14.1M -627,760 -51%
Northern Trust
41
Northern Trust
Illinois
$11.2M +$200K +8,880 +2%
Susquehanna International Group
42
Susquehanna International Group
Pennsylvania
$11M +$8.39M +372,482 +245%
JF
43
Jump Financial
Illinois
$10.6M +$8.74M +388,215 +335%
Connor, Clark & Lunn Investment Management (CC&L)
44
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$10.5M +$5.34M +237,053 +90%
SSA
45
Schonfeld Strategic Advisors
New York
$10.4M -$5.56M -246,881 -33%
BNP Paribas Financial Markets
46
BNP Paribas Financial Markets
France
$10.3M -$9.28M -412,267 -46%
IC
47
Ikarian Capital
Texas
$10.1M +$10.6M +469,900 +3,708%
Adage Capital Partners
48
Adage Capital Partners
Massachusetts
$10.1M +$4.5M +200,000 +71%
Manulife (Manufacturers Life Insurance)
49
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$9.45M +$2.7M +119,950 +36%
Squarepoint
50
Squarepoint
New York
$9.31M +$1.21M +53,940 +14%
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RARE Hedge Fund Activity: Q1 2026 in Review

295 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in Ultragenyx Pharmaceutical (RARE) for Q1 2026, worth a combined $2.05B — down 5% from $2.16B a quarter earlier.

Buyers outnumbered sellers: 62 funds opened new RARE positions and 48 closed out — a net gain of 14 holders — while 125 added to existing stakes and 83 trimmed.

The largest buyer was AQR Capital Management, adding an estimated $72.5M. The largest seller was JP Morgan Chase, cutting an estimated $84M.

  • 295 institutional investors held Ultragenyx Pharmaceutical (RARE) as of Q1 2026, up from 287 in Q4 2025.
  • Funds reported $2.05B of Ultragenyx Pharmaceutical stock for Q1 2026, down 5% quarter-over-quarter.
  • 62 funds opened new Ultragenyx Pharmaceutical positions in Q1 2026 and 48 closed out, a net change of +14 holders.
  • The largest Ultragenyx Pharmaceutical buyer in Q1 2026 was AQR Capital Management, an estimated $72.5M added.
  • The largest Ultragenyx Pharmaceutical seller in Q1 2026 was JP Morgan Chase, an estimated $84M sold.

Based on aggregated 13F filings for Q1 2026.