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Ultragenyx Pharmaceutical
RARE

Overview Fund Activity

307 hedge funds and large institutions have $3.42B invested in Ultragenyx Pharmaceutical in 2025 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 116 increasing their positions, 108 reducing their positions, and 43 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
307
Holders Change
+10
Holders Change %
+3.37%
% of All Funds
4.12%
Holding in Top 10
6
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-14.29%
% of All Funds
0.08%
New
54
Increased
116
Reduced
108
Closed
43
Calls
$149M
Puts
$87.7M
Net Calls
+$60.8M
Net Calls Change
+$59.2M

Top Buyers

1
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
$119M
2
Fidelity Investments
Fidelity Investments
Massachusetts
$94.7M
3
BBA
Baker Bros. Advisors
New York
$101M
4
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
$42.3M
5
FCM
Farallon Capital Management
California
$32.7M

Top Sellers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
$55.6M
2
Wellington Management Group
Wellington Management Group
Massachusetts
$68.1M
3
ACA
Avoro Capital Advisors
New York
$12M
4
VPC
Vestal Point Capital
New York
$0
5
Invesco
Invesco
Georgia
$26.3M
Name Holding Trade Value Shares
Change 		Shares
Change %
Norges Bank
26
Norges Bank
Norway
$35.8M +$35.8M +983,638 New
FCM
27
Farallon Capital Management
California
$32.7M +$32.7M +898,000 New
Two Sigma Advisers
28
Two Sigma Advisers
New York
$31.3M -$2.79M -76,800 -8%
Invesco
29
Invesco
Georgia
$26.3M -$17.8M -489,167 -40%
Morgan Stanley
30
Morgan Stanley
New York
$23.2M +$454K +12,479 +2%
Bank of America
31
Bank of America
North Carolina
$23.2M +$3.99M +109,710 +21%
EHI
32
Eagle Health Investments
Connecticut
$22.8M – – –
Charles Schwab
33
Charles Schwab
California
$22.4M +$831K +22,848 +4%
DCM
34
Driehaus Capital Management
Illinois
$22M -$8.95M -246,250 -29%
Two Sigma Investments
35
Two Sigma Investments
New York
$21M -$2.05M -56,251 -9%
SSA
36
Schonfeld Strategic Advisors
New York
$20.6M -$9.35M -257,243 -31%
PCH
37
Polar Capital Holdings
United Kingdom
$20M -$3.64M -100,000 -15%
Loomis, Sayles & Company
38
Loomis, Sayles & Company
Massachusetts
$20M -$434K -11,941 -2%
FLAM
39
First Light Asset Management
Minnesota
$19.9M -$3.06M -84,128 -13%
D.E. Shaw & Co
40
D.E. Shaw & Co
New York
$19.7M -$568K -15,616 -3%
CS
41
Candriam SCA
Luxembourg
$19.1M -$7.34M -201,750 -28%
FCM
42
Frontier Capital Management
Massachusetts
$19.1M +$19.1M +525,464 New
Point72 Asset Management
43
Point72 Asset Management
Connecticut
$18.8M -$16.7M -460,084 -47%
NL
44
Nuveen LLC
North Carolina
$18.4M -$487K -13,391 -3%
Aberdeen Group
45
Aberdeen Group
United Kingdom
$18.2M +$805K +22,152 +5%
Northern Trust
46
Northern Trust
Illinois
$17.9M -$2.72M -74,919 -13%
Massachusetts Financial Services
47
Massachusetts Financial Services
Massachusetts
$17.7M -$560K -15,391 -3%
Millennium Management
48
Millennium Management
New York
$17.7M -$8.22M -226,052 -32%
GKIM
49
GW&K Investment Management
Massachusetts
$17.5M -$761K -20,923 -4%
Franklin Resources
50
Franklin Resources
California
$17.3M -$4.56M -125,290 -21%
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