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Ultragenyx Pharmaceutical
RARE

Overview Fund Activity

297 hedge funds and large institutions have $3.22B invested in Ultragenyx Pharmaceutical in 2025 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 125 increasing their positions, 104 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
297
Holders Change
-13
Holders Change %
-4.19%
% of All Funds
4.03%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.1%
New
34
Increased
125
Reduced
104
Closed
44
Calls
$43.9M
Puts
$42.2M
Net Calls
+$1.65M
Net Calls Change
+$8.06M

Top Buyers

1
Adage Capital Partners
Adage Capital Partners
Massachusetts
+$35M
2
SCM
Suvretta Capital Management
New York
+$31.6M
3
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
+$25.6M
4
DTC
Deep Track Capital
Connecticut
+$25.2M
5
PCH
Polar Capital Holdings
United Kingdom
+$23.6M

Top Sellers

1
VPC
Vestal Point Capital
New York
-$36.2M
2
Marshall Wace
Marshall Wace
United Kingdom
-$26M
3
First Trust Advisors
First Trust Advisors
Illinois
-$19.1M
4
Invesco
Invesco
Georgia
-$17.6M
5
AllianceBernstein
AllianceBernstein
Tennessee
-$13.8M
Name Holding Trade Value Shares
Change 		Shares
Change %
ACA
26
Avoro Capital Advisors
New York
$30.1M – – –
SSA
27
Schonfeld Strategic Advisors
New York
$29.9M +$2.79M +76,989 +10%
CS
28
Candriam SCA
Luxembourg
$26.4M +$1.95M +53,760 +8%
Millennium Management
29
Millennium Management
New York
$25.8M +$549K +15,157 +2%
Bank of New York Mellon
30
Bank of New York Mellon
New York
$25.2M -$1.55M -42,812 -6%
FLSM
31
Frazier Life Sciences Management
California
$23.9M – – –
PCH
32
Polar Capital Holdings
United Kingdom
$23.6M +$23.6M +651,383 New
Two Sigma Investments
33
Two Sigma Investments
New York
$22.9M +$659K +18,204 +3%
FLAM
34
First Light Asset Management
Minnesota
$22.9M -$4.76M -131,574 -17%
EHI
35
Eagle Health Investments
Connecticut
$22.7M – – –
Morgan Stanley
36
Morgan Stanley
New York
$22.7M +$1.02M +28,211 +5%
Franklin Resources
37
Franklin Resources
California
$21.7M +$6.27M +173,087 +41%
Charles Schwab
38
Charles Schwab
California
$21.5M -$743K -20,512 -3%
Northern Trust
39
Northern Trust
Illinois
$20.6M +$1.43M +39,424 +7%
Loomis, Sayles & Company
40
Loomis, Sayles & Company
Massachusetts
$20.3M +$20.3M +561,479 New
D.E. Shaw & Co
41
D.E. Shaw & Co
New York
$20.1M +$9.79M +270,338 +94%
Bank of America
42
Bank of America
North Carolina
$19.1M +$5.05M +139,478 +36%
FAM
43
Fred Alger Management
New York
$19M +$2.11M +58,372 +13%
NL
44
Nuveen LLC
North Carolina
$18.8M +$18.8M +518,543 New
EA
45
Emerald Advisers
Pennsylvania
$18.7M -$76K -2,100 -0.4%
GKIM
46
GW&K Investment Management
Massachusetts
$18.2M -$266K -7,334 -1%
Massachusetts Financial Services
47
Massachusetts Financial Services
Massachusetts
$18.2M +$47.3K +1,306 +0.3%
VPC
48
Vestal Point Capital
New York
$18.1M -$36.2M -1,000,000 -67%
Goldman Sachs
49
Goldman Sachs
New York
$17.4M -$2.66M -73,401 -13%
Aberdeen Group
50
Aberdeen Group
United Kingdom
$17.3M +$5.86M +161,779 +51%
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