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Ultragenyx Pharmaceutical

285 hedge funds and large institutions have $2.16B invested in Ultragenyx Pharmaceutical in 2025 Q4 according to their latest regulatory filings, with 56 funds opening new positions, 110 increasing their positions, 91 reducing their positions, and 65 closing their positions.

New
Increased
Maintained
Reduced
Closed

more call options, than puts

Call options by funds: $ | Put options by funds: $

more repeat investments, than reductions

Existing positions increased: | Existing positions reduced:

less ownership

Funds ownership:

less funds holding

Funds holding:

14% less first-time investments, than exits

New positions opened: 56 | Existing positions closed: 65

25% less capital invested

Capital invested by funds: $2.87B → $2.16B (-$711M)

50% less funds holding in top 10

Funds holding in top 10: 42 (-2)

Holders
285
Holders Change
Holders Change %
% of All Funds
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
Increased
Reduced
Closed
Calls
$75.9M
Puts
$47.6M
Net Calls
Net Calls Change

Top Buyers

1 +$65.6M
2 +$30.1M
3 +$29.5M
4
Millennium Management
Millennium Management
New York
+$25.7M
5
Jane Street
Jane Street
New York
+$21.9M

Top Sellers

1 -$152M
2 -$31.1M
3 -$29.6M
4
T. Rowe Price Associates
T. Rowe Price Associates
Maryland
-$24.9M
5
VPC
Vestal Point Capital
New York
-$22.6M
Name Holding Trade Value Shares
Change
Change in
Stake
WWA
276
Wealth Watch Advisors
Colorado
$299
WA
277
WPG Advisers
Maryland
$253
TFA
278
Transamerica Financial Advisors
Florida
$207
GFA
279
Godfrey Financial Associates
New York
$184
TRCT
280
Tower Research Capital (TRC)
New York
$161
TM
281
Torren Management
California
$161
SC
282
SouthState Corp
Florida
$115
CJ
283
Caitlin John
Michigan
$115
TFM
284
TFC Financial Management
Massachusetts
$46
DF
285
Dunhill Financial
United Kingdom
$38
FLSM
286
Frazier Life Sciences Management
California
VPC
287
Vestal Point Capital
New York
EHI
288
Eagle Health Investments
Connecticut
DCM
289
Driehaus Capital Management
Illinois
B
290
Braidwell
Connecticut
Alyeska Investment Group
291
Alyeska Investment Group
Illinois
Federated Hermes
292
Federated Hermes
Pennsylvania
MB
293
MPM BioImpact
Massachusetts
FLAM
294
First Light Asset Management
Minnesota
Hudson Bay Capital Management
295
Hudson Bay Capital Management
Connecticut
YCM
296
Yiheng Capital Management
California
Macquarie Group
297
Macquarie Group
Australia
ClearBridge Investments
298
ClearBridge Investments
New York
GGHC
299
Gilder Gagnon Howe & Co
New York
RPAM
300
Rhenman & Partners Asset Management
Sweden