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PTC Therapeutics

261 hedge funds and large institutions have $4.02B invested in PTC Therapeutics in 2025 Q1 according to their latest regulatory filings, with 50 funds opening new positions, 85 increasing their positions, 94 reducing their positions, and 27 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 36 (+3)

85% more first-time investments, than exits

New positions opened: 50 | Existing positions closed: 27

27% more call options, than puts

Call options by funds: $15.8M | Put options by funds: $12.5M

15% more capital invested

Capital invested by funds: $3.51B → $4.02B (+$516M)

9% more funds holding

Funds holding: 240261 (+21)

0.9% less ownership

Funds ownership: 100.76%99.87% (-0.9%)

10% less repeat investments, than reductions

Existing positions increased: 85 | Existing positions reduced: 94

Holders
261
Holders Change
+21
Holders Change %
+8.75%
% of All Funds
3.5%
Holding in Top 10
6
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+100%
% of All Funds
0.08%
New
50
Increased
85
Reduced
94
Closed
27
Calls
$15.8M
Puts
$12.5M
Net Calls
+$3.3M
Net Calls Change
+$20.9M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$439M -$28.5M -571,450 -6%
BlackRock
2
BlackRock
New York
$396M -$6.52M -130,584 -2%
RI
3
RTW Investments
New York
$381M +$4.49M +90,000 +1%
AC
4
Armistice Capital
New York
$277M -$47.1M -943,157 -15%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$276M +$31.5M +632,049 +13%
Janus Henderson Group
6
Janus Henderson Group
United Kingdom
$158M +$29.5M +590,814 +25%
Toronto Dominion Bank
7
Toronto Dominion Bank
Ontario, Canada
$133M -$33.6M -673,533 -20%
State Street
8
State Street
Massachusetts
$125M -$12.6M -253,100 -9%
Fidelity Investments
9
Fidelity Investments
Massachusetts
$103M +$59.6M +1,193,518 +146%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$95.5M +$3.84M +76,870 +4%
DCM
11
Driehaus Capital Management
Illinois
$77.1M +$23.5M +471,586 +45%
CCM
12
Camber Capital Management
Massachusetts
$76.4M -$84.8M -1,700,000 -53%
D.E. Shaw & Co
13
D.E. Shaw & Co
New York
$73.7M -$4.84M -97,013 -6%
Point72 Asset Management
14
Point72 Asset Management
Connecticut
$70M -$3.48M -69,789 -5%
Franklin Resources
15
Franklin Resources
California
$64.9M -$258K -5,180 -0.4%
UBS Group
16
UBS Group
Switzerland
$64.7M +$9.91M +198,596 +19%
Citadel Advisors
17
Citadel Advisors
Florida
$59.5M +$35.4M +709,606 +155%
Pictet Asset Management
18
Pictet Asset Management
Switzerland
$54M +$15.3M +306,070 +42%
N
19
Nuveen
North Carolina
$51.4M -$3.42M -68,626 -6%
TCM
20
Tang Capital Management
California
$51M +$15M +300,000 +43%
Morgan Stanley
21
Morgan Stanley
New York
$48.4M -$6.21M -124,383 -12%
Northern Trust
22
Northern Trust
Illinois
$37.9M +$800K +16,035 +2%
Marshall Wace
23
Marshall Wace
United Kingdom
$37.8M +$37M +741,002 New
Renaissance Technologies
24
Renaissance Technologies
New York
$34.2M +$853K +17,100 +3%
Charles Schwab
25
Charles Schwab
California
$33.7M -$1.18M -23,635 -3%

PTCT Hedge Fund Activity: Q1 2025 in Review

261 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in PTC Therapeutics (PTCT) for Q1 2025, worth a combined $4.02B — up 15% from $3.51B a quarter earlier.

Buyers outnumbered sellers: 50 funds opened new PTCT positions and 27 closed out — a net gain of 23 holders — while 85 added to existing stakes and 94 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $59.6M. The largest seller was Camber Capital Management, cutting an estimated $84.8M.

  • 261 institutional investors held PTC Therapeutics (PTCT) as of Q1 2025, up from 240 in Q4 2024.
  • Funds reported $4.02B of PTC Therapeutics stock for Q1 2025, up 15% quarter-over-quarter.
  • 50 funds opened new PTC Therapeutics positions in Q1 2025 and 27 closed out, a net change of +23 holders.
  • The largest PTC Therapeutics buyer in Q1 2025 was Fidelity Investments, an estimated $59.6M added.
  • The largest PTC Therapeutics seller in Q1 2025 was Camber Capital Management, an estimated $84.8M sold.

Based on aggregated 13F filings for Q1 2025.