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PTC Therapeutics

293 hedge funds and large institutions have $5.07B invested in PTC Therapeutics in 2025 Q3 according to their latest regulatory filings, with 55 funds opening new positions, 101 increasing their positions, 105 reducing their positions, and 41 closing their positions.

New
Increased
Maintained
Reduced
Closed

265% more call options, than puts

Call options by funds: $50.2M | Put options by funds: $13.8M

80% more funds holding in top 10

Funds holding in top 10: 59 (+4)

34% more first-time investments, than exits

New positions opened: 55 | Existing positions closed: 41

30% more capital invested

Capital invested by funds: $3.9B → $5.07B (+$1.17B)

4% more funds holding

Funds holding: 283293 (+10)

3.25% more ownership

Funds ownership: 100.83%104.08% (+3.3%)

4% less repeat investments, than reductions

Existing positions increased: 101 | Existing positions reduced: 105

Holders
293
Holders Change
+10
Holders Change %
+3.53%
% of All Funds
3.85%
Holding in Top 10
9
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+80%
% of All Funds
0.12%
New
55
Increased
101
Reduced
105
Closed
41
Calls
$50.2M
Puts
$13.8M
Net Calls
+$36.4M
Net Calls Change
+$31.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Dimensional Fund Advisors
26
Dimensional Fund Advisors
Texas
$47.4M +$12.8M +245,774 +47%
Northern Trust
27
Northern Trust
Illinois
$45.3M -$84.5K -1,622 -0.2%
N
28
Nuveen
North Carolina
$44.3M -$12.9M -247,690 -26%
Charles Schwab
29
Charles Schwab
California
$43.1M -$258K -4,946 -0.7%
Pacer Advisors
30
Pacer Advisors
Pennsylvania
$30.9M -$12.3M -236,851 -32%
JP Morgan Chase
31
JP Morgan Chase
New York
$30.1M -$5.76M -110,626 -18%
Rockefeller Capital Management
32
Rockefeller Capital Management
New York
$29.1M +$556K +10,679 +2%
T. Rowe Price Associates
33
T. Rowe Price Associates
Maryland
$28.1M +$246K +4,728 +1%
UBS Group
34
UBS Group
Switzerland
$27.8M -$6.6M -126,741 -22%
MB
35
MPM BioImpact
Massachusetts
$26.9M
Qube Research & Technologies (QRT)
36
Qube Research & Technologies (QRT)
United Kingdom
$26.4M +$4.83M +92,771 +27%
Manulife (Manufacturers Life Insurance)
37
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$26.1M +$20M +383,307 +919%
Morgan Stanley
38
Morgan Stanley
New York
$25.7M -$38.7M -743,922 -64%
Lord, Abbett & Co
39
Lord, Abbett & Co
New Jersey
$23.2M -$333K -6,394 -2%
Boston Partners
40
Boston Partners
Massachusetts
$22.2M +$18.8M +361,664 New
PAM
41
Panagora Asset Management
Massachusetts
$21.4M +$3.25M +62,309 +22%
AQR Capital Management
42
AQR Capital Management
Connecticut
$20.3M -$10.7M -205,860 -38%
Arrowstreet Capital
43
Arrowstreet Capital
Massachusetts
$19.9M +$15.1M +289,548 +852%
Invesco
44
Invesco
Georgia
$19.2M +$512K +9,823 +3%
Adage Capital Partners
45
Adage Capital Partners
Massachusetts
$17.9M -$16.4M -314,905 -52%
Ensign Peak Advisors
46
Ensign Peak Advisors
Utah
$17.7M +$1.07M +20,550 +8%
VOYA Investment Management
47
VOYA Investment Management
Georgia
$17.5M +$1.27M +24,399 +9%
IC
48
Ikarian Capital
Texas
$17.2M +$14.6M +280,551 New
Bank of New York Mellon
49
Bank of New York Mellon
New York
$16.8M +$360K +6,905 +3%
Man Group
50
Man Group
United Kingdom
$16.3M -$21.2M -406,332 -61%

PTCT Hedge Fund Activity: Q3 2025 in Review

293 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in PTC Therapeutics (PTCT) for Q3 2025, worth a combined $5.07B — up 30% from $3.9B a quarter earlier.

Buyers outnumbered sellers: 55 funds opened new PTCT positions and 41 closed out — a net gain of 14 holders — while 101 added to existing stakes and 105 trimmed.

The largest buyer was Jefferies Financial Group, opening a new position worth an estimated $82.5M. The largest seller was Armistice Capital, cutting an estimated $76M.

  • 293 institutional investors held PTC Therapeutics (PTCT) as of Q3 2025, up from 283 in Q2 2025.
  • Funds reported $5.07B of PTC Therapeutics stock for Q3 2025, up 30% quarter-over-quarter.
  • 55 funds opened new PTC Therapeutics positions in Q3 2025 and 41 closed out, a net change of +14 holders.
  • The largest PTC Therapeutics buyer in Q3 2025 was Jefferies Financial Group, an estimated $82.5M added.
  • The largest PTC Therapeutics seller in Q3 2025 was Armistice Capital, an estimated $76M sold.

Based on aggregated 13F filings for Q3 2025.