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PTC Therapeutics

284 hedge funds and large institutions have $3.9B invested in PTC Therapeutics in 2025 Q2 according to their latest regulatory filings, with 60 funds opening new positions, 111 increasing their positions, 80 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

71% more first-time investments, than exits

New positions opened: 60 | Existing positions closed: 35

70% more call options, than puts

Call options by funds: $13.1M | Put options by funds: $7.7M

39% more repeat investments, than reductions

Existing positions increased: 111 | Existing positions reduced: 80

9% more funds holding

Funds holding: 261284 (+23)

0.97% more ownership

Funds ownership: 99.87%100.83% (+0.97%)

3% less capital invested

Capital invested by funds: $4.02B → $3.9B (-$121M)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

Holders
284
Holders Change
+23
Holders Change %
+8.81%
% of All Funds
3.74%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.07%
New
60
Increased
111
Reduced
80
Closed
35
Calls
$13.1M
Puts
$7.7M
Net Calls
+$5.37M
Net Calls Change
+$2.07M
Name Holding Trade Value Shares
Change
Change in
Stake
Man Group
26
Man Group
United Kingdom
$32.8M +$19.5M +410,653 +157%
HRCM
27
Hood River Capital Management
Florida
$31.1M +$26.2M +552,130 +654%
Assenagon Asset Management
28
Assenagon Asset Management
Luxembourg
$30.8M +$13.9M +293,662 +87%
Adage Capital Partners
29
Adage Capital Partners
Massachusetts
$29.6M +$518K +10,905 +2%
JP Morgan Chase
30
JP Morgan Chase
New York
$29.4M -$91.2K -1,922 -0.3%
UBS Group
31
UBS Group
Switzerland
$28.3M -$32.8M -690,697 -54%
Marshall Wace
32
Marshall Wace
United Kingdom
$26.3M -$9.65M -203,226 -27%
AQR Capital Management
33
AQR Capital Management
Connecticut
$26.2M +$5.89M +124,093 +30%
Dimensional Fund Advisors
34
Dimensional Fund Advisors
Texas
$25.8M -$1.63M -34,435 -6%
Rockefeller Capital Management
35
Rockefeller Capital Management
New York
$22.6M +$368K +7,751 +2%
T. Rowe Price Associates
36
T. Rowe Price Associates
Maryland
$22.2M -$710K -14,952 -3%
MB
37
MPM BioImpact
Massachusetts
$21.4M -$71.2K -1,500 -0.3%
Susquehanna International Group
38
Susquehanna International Group
Pennsylvania
$21.1M +$15.5M +325,663 +307%
PAI
39
Palo Alto Investors
California
$19.9M +$108K +2,273 +0.6%
Lord, Abbett & Co
40
Lord, Abbett & Co
New Jersey
$18.8M +$18.3M +384,447 New
Millennium Management
41
Millennium Management
New York
$18.8M +$7.57M +159,563 +71%
SI
42
Sofinnova Investments
California
$18.4M -$9.66M -203,400 -35%
Qube Research & Technologies (QRT)
43
Qube Research & Technologies (QRT)
United Kingdom
$16.5M +$1.97M +41,596 +14%
Invesco
44
Invesco
Georgia
$14.8M -$337K -7,095 -2%
Citigroup
45
Citigroup
New York
$14.1M -$820K -17,281 -6%
PAM
46
Panagora Asset Management
Massachusetts
$14M -$1.22M -25,720 -8%
Barclays
47
Barclays
United Kingdom
$13.7M +$7M +147,473 +111%
TI
48
Trexquant Investment
Connecticut
$13.3M +$3.75M +78,975 +41%
Royal Bank of Canada
49
Royal Bank of Canada
Ontario, Canada
$13.3M +$12.8M +270,503 +14,733%
Ensign Peak Advisors
50
Ensign Peak Advisors
Utah
$13.1M -$287K -6,050 -2%

PTCT Hedge Fund Activity: Q2 2025 in Review

284 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in PTC Therapeutics (PTCT) for Q2 2025, worth a combined $3.9B — down 3% from $4.02B a quarter earlier.

Buyers outnumbered sellers: 60 funds opened new PTCT positions and 35 closed out — a net gain of 25 holders — while 111 added to existing stakes and 80 trimmed.

The largest buyer was D.E. Shaw & Co, adding an estimated $47.1M. The largest seller was Camber Capital Management, exiting entirely with an estimated $76.4M sold.

  • 284 institutional investors held PTC Therapeutics (PTCT) as of Q2 2025, up from 261 in Q1 2025.
  • Funds reported $3.9B of PTC Therapeutics stock for Q2 2025, down 3% quarter-over-quarter.
  • 60 funds opened new PTC Therapeutics positions in Q2 2025 and 35 closed out, a net change of +25 holders.
  • The largest PTC Therapeutics buyer in Q2 2025 was D.E. Shaw & Co, an estimated $47.1M added.
  • The largest PTC Therapeutics seller in Q2 2025 was Camber Capital Management, an estimated $76.4M sold.

Based on aggregated 13F filings for Q2 2025.