|
1
|
|
$206M
|
–
|
–
|
–
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$37.2M
|
-$11.5M
|
-745,843
|
-23%
|
|
|
3
|
|
$21.6M
|
+$4.81M
|
+312,364
|
+28%
|
|
|
4
|
Adage Capital Partners
Boston,
Massachusetts
|
$20.8M
|
+$13.9M
|
+900,000
|
+181%
|
|
|
5
|
Citadel Advisors
Miami,
Florida
|
$17.5M
|
+$44.1K
|
+2,866
|
+0.2%
|
|
|
6
|
Boxer Capital
San Diego,
California
|
$16.7M
|
–
|
–
|
–
|
|
|
7
|
Avidity Partners Management
Dallas,
Texas
|
$15.3M
|
+$15.8M
|
+1,028,800
|
New
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$11.1M
|
-$718K
|
-46,600
|
-6%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$10.9M
|
+$5.61M
|
+364,402
|
+100%
|
|
|
10
|
|
$5.51M
|
+$2.62M
|
+170,000
|
+85%
|
|
|
11
|
|
$5.5M
|
+$4.5M
|
+292,096
|
+380%
|
|
|
12
|
EcoR1 Capital
San Francisco,
California
|
$5.47M
|
-$29M
|
-1,881,088
|
-84%
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$4.9M
|
+$1.2M
|
+77,603
|
+31%
|
|
|
14
|
Clal Insurance
Tel-Aviv,
Israel
|
$4.35M
|
–
|
–
|
–
|
|
|
15
|
Bank of America
Charlotte,
North Carolina
|
$3.81M
|
-$49.2K
|
-3,194
|
-1%
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$3.65M
|
+$548K
|
+35,594
|
+17%
|
|
|
17
|
Bank of New York Mellon
New York
|
$2.94M
|
-$426K
|
-27,686
|
-12%
|
|
|
18
|
Omega Fund Management
Boston,
Massachusetts
|
$2.79M
|
-$1.31M
|
-85,269
|
-31%
|
|
|
19
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$2.65M
|
+$2.73M
|
+177,547
|
New
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$2.44M
|
+$136K
|
+8,856
|
+6%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$2.04M
|
-$315K
|
-20,477
|
-13%
|
|
|
22
|
|
$1.99M
|
–
|
–
|
–
|
|
|
23
|
Millennium Management
New York
|
$1.9M
|
+$479K
|
+31,124
|
+32%
|
|
|
24
|
DAFNA Capital Management
Los Angeles,
California
|
$1.12M
|
–
|
–
|
–
|
|
|
25
|
UBS Group
Zurich,
Switzerland
|
$1.09M
|
-$25.4K
|
-1,652
|
-2%
|
|
