|
1
|
|
$219M
|
–
|
–
|
–
|
|
|
2
|
RA Capital Management
Boston,
Massachusetts
|
$53.2M
|
–
|
–
|
–
|
|
|
3
|
EcoR1 Capital
San Francisco,
California
|
$35.6M
|
-$1.84M
|
-144,250
|
-6%
|
|
|
4
|
Citadel Advisors
Miami,
Florida
|
$18.5M
|
+$1.28M
|
+100,003
|
+9%
|
|
|
5
|
Boxer Capital
San Diego,
California
|
$17.8M
|
–
|
–
|
–
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$13.8M
|
–
|
–
|
–
|
|
|
7
|
|
$11.3M
|
+$3.41M
|
+267,040
|
+60%
|
|
|
8
|
Omega Fund Management
Boston,
Massachusetts
|
$10.6M
|
-$13
|
-1
|
-0%
|
|
|
9
|
BVF Inc
San Francisco,
California
|
$10.4M
|
–
|
–
|
–
|
|
|
10
|
Adage Capital Partners
Boston,
Massachusetts
|
$7.85M
|
-$204K
|
-16,000
|
-3%
|
|
|
11
|
Point72 Asset Management
Stamford,
Connecticut
|
$5.8M
|
+$4.67M
|
+366,324
|
New
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$4.84M
|
+$911K
|
+71,431
|
+30%
|
|
|
13
|
Bank of America
Charlotte,
North Carolina
|
$4.39M
|
+$470K
|
+36,821
|
+15%
|
|
|
14
|
Bank of New York Mellon
New York
|
$3.38M
|
+$43.6K
|
+3,419
|
+2%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$1.66M
|
+$546K
|
+42,767
|
+69%
|
|
|
16
|
Geode Capital Management
Boston,
Massachusetts
|
$1.56M
|
+$218K
|
+17,099
|
+21%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$1.29M
|
-$28.9K
|
-2,269
|
-3%
|
|
|
18
|
UBS Group
Zurich,
Switzerland
|
$1.22M
|
+$979K
|
+76,764
|
New
|
|
|
19
|
DAFNA Capital Management
Los Angeles,
California
|
$1.19M
|
–
|
–
|
–
|
|
|
20
|
Altshuler Shaham
Tel Aviv,
Israel
|
$799K
|
–
|
–
|
–
|
|
|
21
|
|
$319K
|
+$257K
|
+20,154
|
New
|
|
|
22
|
Clal Insurance
Tel-Aviv,
Israel
|
$292K
|
-$3.67M
|
-287,378
|
-98%
|
|
|
23
|
Nuveen
Charlotte,
North Carolina
|
$282K
|
-$83.9K
|
-6,576
|
-27%
|
|
|
24
|
Charles Schwab
San Francisco,
California
|
$248K
|
–
|
–
|
–
|
|
|
25
|
|
$247K
|
+$199K
|
+15,579
|
New
|
|
