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Protalix BioTherapeutics
PLX

Overview Fund Activity

63 hedge funds and large institutions have $21M invested in Protalix BioTherapeutics in 2025 Q1 according to their latest regulatory filings, with 23 funds opening new positions, 19 increasing their positions, 10 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
63
Holders Change
+18
Holders Change %
+40%
% of All Funds
0.86%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
23
Increased
19
Reduced
10
Closed
5
Calls
$838K
Puts
$166K
Net Calls
+$672K
Net Calls Change
+$584K

Top Buyers

1
Susquehanna International Group
Susquehanna International Group
Pennsylvania
$2.2M
2
Millennium Management
Millennium Management
New York
$2.47M
3
Marshall Wace
Marshall Wace
United Kingdom
$1.57M
4
Connor, Clark & Lunn Investment Management (CC&L)
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$1.24M
5
Goldman Sachs
Goldman Sachs
New York
$741K

Top Sellers

1
Citadel Advisors
Citadel Advisors
Florida
$7.21K
2
GCP
GSA Capital Partners
United Kingdom
$536K
3
Morgan Stanley
Morgan Stanley
New York
$214K
4
Northern Trust
Northern Trust
Illinois
$1.75M
5
Bank of America
Bank of America
North Carolina
$16
Name Holding Trade Value Shares
Change 		Shares
Change %
OGF
26
Orin Green Financial
California
$128K +$128K +50,000 New
LP
27
LMR Partners
United Kingdom
$126K +$126K +49,025 New
KAS
28
Kestra Advisory Services
Texas
$114K +$78.1K +30,500 +218%
XT
29
XTX Topco
Cayman Islands
$107K +$107K +41,826 New
Prudential Financial
30
Prudential Financial
New Jersey
$93.2K – – –
Two Sigma Advisers
31
Two Sigma Advisers
New York
$84.5K +$84.5K +33,015 New
Creative Planning
32
Creative Planning
Kansas
$83.8K +$83.8K +32,740 New
CFM
33
Catalyst Funds Management
Australia
$69.5K +$43.4K +16,939 +166%
CPA
34
Capital Performance Advisors
California
$66.5K – – –
HSBC Holdings
35
HSBC Holdings
United Kingdom
$64.3K -$36.5K -14,488 -36%
Barclays
36
Barclays
United Kingdom
$62K -$25.5K -10,013 -29%
ACA
37
Aptus Capital Advisors
Alabama
$61.3K +$1.47K +575 +2%
CM
38
Capula Management
Cayman Islands
$40.2K +$40.2K +15,690 New
Lido Advisors
39
Lido Advisors
California
$39.8K – – –
Capstone Investment Advisors
40
Capstone Investment Advisors
New York
$39.3K +$39.3K +15,336 New
Raymond James Financial
41
Raymond James Financial
Florida
$38.8K +$38.8K +15,174 New
NA
42
NewEdge Advisors
Louisiana
$38.6K +$38.6K +15,080 New
BHCM
43
Brevan Howard Capital Management
Jersey
$34.5K +$34.5K +13,474 New
AS
44
Altshuler Shaham
Israel
$31.1K – – –
Hudson Bay Capital Management
45
Hudson Bay Capital Management
Connecticut
$30.7K +$30.7K +12,000 New
HIM
46
Harbour Investment Management
Washington
$25.9K – – –
Acadian Asset Management
47
Acadian Asset Management
Massachusetts
$24K +$24K +9,691 New
TWC
48
TD Waterhouse Canada
Ontario, Canada
$15.2K – – –
PD
49
Point72 (DIFC)
United Arab Emirates
$14.4K +$12.1K +4,722 +524%
Citadel Advisors
50
Citadel Advisors
Florida
$7.21K -$366K -142,969 -98%
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