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Protalix BioTherapeutics

63 hedge funds and large institutions have $21M invested in Protalix BioTherapeutics in 2025 Q1 according to their latest regulatory filings, with 23 funds opening new positions, 19 increasing their positions, 10 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

405% more call options, than puts

Call options by funds: $838K | Put options by funds: $166K

360% more first-time investments, than exits

New positions opened: 23 | Existing positions closed: 5

150% more capital invested

Capital invested by funds: $8.4M → $21M (+$12.6M)

90% more repeat investments, than reductions

Existing positions increased: 19 | Existing positions reduced: 10

40% more funds holding

Funds holding: 4563 (+18)

4.52% more ownership

Funds ownership: 5.97%10.49% (+4.5%)

Holders
63
Holders Change
+18
Holders Change %
+40%
% of All Funds
0.84%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
23
Increased
19
Reduced
10
Closed
5
Calls
$838K
Puts
$166K
Net Calls
+$672K
Net Calls Change
+$584K
Name Holding Trade Value Shares
Change
Change in
Stake
OGF
26
Orin Green Financial
California
$128K +$119K +50,000 New
LP
27
LMR Partners
United Kingdom
$126K +$117K +49,025 New
KAS
28
Kestra Advisory Services
Texas
$114K +$72.8K +30,500 +218%
XT
29
XTX Topco
Cayman Islands
$107K +$99.9K +41,826 New
Prudential Financial
30
Prudential Financial
New Jersey
$93.2K
Two Sigma Advisers
31
Two Sigma Advisers
New York
$84.5K +$78.8K +33,015 New
Creative Planning
32
Creative Planning
Kansas
$83.8K +$78.2K +32,740 New
CFM
33
Catalyst Funds Management
Australia
$69.5K +$40.5K +16,939 +166%
CPA
34
Capital Performance Advisors
California
$66.5K
HSBC Holdings
35
HSBC Holdings
United Kingdom
$64.3K -$34.6K -14,488 -36%
Barclays
36
Barclays
United Kingdom
$62.2K -$23.9K -10,013 -29%
ACA
37
Aptus Capital Advisors
Alabama
$61.3K +$1.37K +575 +2%
CM
38
Capula Management
Cayman Islands
$40.2K +$37.5K +15,690 New
Lido Advisors
39
Lido Advisors
California
$39.8K
Capstone Investment Advisors
40
Capstone Investment Advisors
New York
$39.3K +$36.6K +15,336 New
Raymond James Financial
41
Raymond James Financial
Florida
$38.8K +$36.2K +15,174 New
NA
42
NewEdge Advisors
Louisiana
$38.6K +$36K +15,080 New
BHCM
43
Brevan Howard Capital Management
Jersey
$34.5K +$32.2K +13,474 New
AS
44
Altshuler Shaham
Israel
$31.1K
Hudson Bay Capital Management
45
Hudson Bay Capital Management
Connecticut
$30.7K +$28.7K +12,000 New
HIM
46
Harbour Investment Management
Washington
$25.9K
Acadian Asset Management
47
Acadian Asset Management
Massachusetts
$24K +$23.1K +9,691 New
TWC
48
TD Waterhouse Canada
Ontario, Canada
$15.2K
PD
49
Point72 (DIFC)
United Arab Emirates
$14.4K +$11.3K +4,722 +524%
Citadel Advisors
50
Citadel Advisors
Florida
$7.21K -$341K -142,969 -98%

PLX Hedge Fund Activity: Q1 2025 in Review

63 of the 7,458 institutional investors tracked by Wall St. Rank reported a position in Protalix BioTherapeutics (PLX) for Q1 2025, worth a combined $21M — up 150% from $8.4M a quarter earlier.

Buyers outnumbered sellers: 23 funds opened new PLX positions and 5 closed out — a net gain of 18 holders — while 19 added to existing stakes and 10 trimmed.

The largest buyer was Susquehanna International Group, opening a new position worth an estimated $2.05M. The largest seller was Citadel Advisors, cutting an estimated $341K.

  • 63 institutional investors held Protalix BioTherapeutics (PLX) as of Q1 2025, up from 45 in Q4 2024.
  • Funds reported $21M of Protalix BioTherapeutics stock for Q1 2025, up 150% quarter-over-quarter.
  • 23 funds opened new Protalix BioTherapeutics positions in Q1 2025 and 5 closed out, a net change of +18 holders.
  • The largest Protalix BioTherapeutics buyer in Q1 2025 was Susquehanna International Group, an estimated $2.05M added.
  • The largest Protalix BioTherapeutics seller in Q1 2025 was Citadel Advisors, an estimated $341K sold.

Based on aggregated 13F filings for Q1 2025.