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Pliant Therapeutics

114 hedge funds and large institutions have $59.7M invested in Pliant Therapeutics in 2025 Q2 according to their latest regulatory filings, with 24 funds opening new positions, 30 increasing their positions, 39 reducing their positions, and 50 closing their positions.

New
Increased
Maintained
Reduced
Closed

22% more call options, than puts

Call options by funds: $133K | Put options by funds: $109K

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

10.65% less ownership

Funds ownership: 94.53%83.88% (-11%)

19% less funds holding

Funds holding: 140114 (-26)

23% less repeat investments, than reductions

Existing positions increased: 30 | Existing positions reduced: 39

24% less capital invested

Capital invested by funds: $78.5M → $59.7M (-$18.8M)

52% less first-time investments, than exits

New positions opened: 24 | Existing positions closed: 50

Holders
114
Holders Change
-26
Holders Change %
-18.57%
% of All Funds
1.5%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
24
Increased
30
Reduced
39
Closed
50
Calls
$133K
Puts
$109K
Net Calls
+$24K
Net Calls Change
-$180K
Name Holding Trade Value Shares
Change
Change in
Stake
Invesco
51
Invesco
Georgia
$85.3K +$6.4K +4,531 +7%
QC
52
Quadrature Capital
United Kingdom
$71.3K -$8.91K -6,304 -9%
RC
53
Rangeley Capital
Connecticut
$69.9K +$14.4K +10,220 +20%
AQR Capital Management
54
AQR Capital Management
Connecticut
$62.3K -$26K -18,374 -25%
PAS
55
Point72 Asia (Singapore)
Singapore
$55.7K +$67.8K +48,007 New
DekaBank Deutsche Girozentrale
56
DekaBank Deutsche Girozentrale
Germany
$54K
Royal Bank of Canada
57
Royal Bank of Canada
Ontario, Canada
$51K -$449K -318,070 -88%
VPIM
58
Vanguard Personalized Indexing Management
California
$41.2K +$27.3K +19,320 +119%
CFM
59
Catalyst Funds Management
Australia
$39.5K +$48.1K +34,015 New
OAM
60
Oxford Asset Management
United Kingdom
$38.3K -$18.3K -12,920 -28%
HF
61
HRT Financial
New York
$37K +$45.9K +32,475 New
EGM
62
Engineers Gate Manager
New York
$36.5K +$25.9K +18,300 +139%
Canada Pension Plan Investment Board
63
Canada Pension Plan Investment Board
Ontario, Canada
$35.7K +$43.5K +30,800 New
Tudor Investment Corp
64
Tudor Investment Corp
Connecticut
$34.5K -$287 -203 -0.7%
SG Americas Securities
65
SG Americas Securities
New York
$34K -$15.9K -11,279 -28%
ZIM
66
Zacks Investment Management
Illinois
$30.5K +$37.2K +26,334 New
JF
67
Jump Financial
Illinois
$29.5K +$36K +25,473 New
Citigroup
68
Citigroup
New York
$27.8K -$30.5K -21,619 -47%
TRCT
69
Tower Research Capital (TRC)
New York
$27K +$13.8K +9,794 +72%
Blackstone Inc
70
Blackstone Inc
New York
$25.8K
Universal-Beteiligungs- und Servicegesellschaft
71
Universal-Beteiligungs- und Servicegesellschaft
Germany
$21K
FIM
72
Freedom Investment Management
Connecticut
$20K +$24.3K +17,217 New
Bank of New York Mellon
73
Bank of New York Mellon
New York
$18.6K -$222K -156,990 -91%
Hudson Bay Capital Management
74
Hudson Bay Capital Management
Connecticut
$18.2K -$97.9K -69,290 -82%
DS
75
DRW Securities
Illinois
$18.1K +$22.1K +15,631 New

PLRX Hedge Fund Activity: Q2 2025 in Review

114 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Pliant Therapeutics (PLRX) for Q2 2025, worth a combined $59.7M — down 24% from $78.5M a quarter earlier.

Sellers outnumbered buyers: 50 funds closed out of PLRX and 24 opened new positions — a net loss of 26 holders — while 39 trimmed existing stakes and 30 added.

The largest buyer was Citadel Advisors, adding an estimated $3.33M. The largest seller was BlackRock, cutting an estimated $4.4M.

  • 114 institutional investors held Pliant Therapeutics (PLRX) as of Q2 2025, down from 140 in Q1 2025.
  • Funds reported $59.7M of Pliant Therapeutics stock for Q2 2025, down 24% quarter-over-quarter.
  • 24 funds opened new Pliant Therapeutics positions in Q2 2025 and 50 closed out, a net change of -26 holders.
  • The largest Pliant Therapeutics buyer in Q2 2025 was Citadel Advisors, an estimated $3.33M added.
  • The largest Pliant Therapeutics seller in Q2 2025 was BlackRock, an estimated $4.4M sold.

Based on aggregated 13F filings for Q2 2025.