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Phathom Pharmaceuticals

133 hedge funds and large institutions have $734M invested in Phathom Pharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 27 funds opening new positions, 45 increasing their positions, 28 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

4,033% more call options, than puts

Call options by funds: $14.3M | Put options by funds: $346K

145% more first-time investments, than exits

New positions opened: 27 | Existing positions closed: 11

61% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 28

33% more capital invested

Capital invested by funds: $551M → $734M (+$183M)

14% more funds holding

Funds holding: 117133 (+16)

5.63% more ownership

Funds ownership: 82.22%87.86% (+5.6%)

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

Holders
133
Holders Change
+16
Holders Change %
+13.68%
% of All Funds
1.75%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
27
Increased
45
Reduced
28
Closed
11
Calls
$14.3M
Puts
$346K
Net Calls
+$14M
Net Calls Change
+$10.7M
Name Holding Trade Value Shares
Change
Change in
Stake
FLSM
1
Frazier Life Sciences Management
California
$147M
MVM
2
Medicxi Ventures Management
Jersey
$87.9M
Millennium Management
3
Millennium Management
New York
$59.8M +$29.2M +2,830,954 +126%
Invesco
4
Invesco
Georgia
$45.5M -$2.84M -275,101 -7%
CG
5
Carlyle Group
District of Columbia
$41.1M
BlackRock
6
BlackRock
New York
$40M +$898K +86,976 +3%
Vanguard Group
7
Vanguard Group
Pennsylvania
$37.8M +$4.42M +428,261 +15%
Ensign Peak Advisors
8
Ensign Peak Advisors
Utah
$29.5M -$172K -16,628 -0.7%
NMC
9
NEA Management Company
Maryland
$23.1M
6CM
10
683 Capital Management
New York
$21.4M -$2.94M -284,620 -14%
WA
11
Wasatch Advisors
Utah
$18.1M +$777K +75,323 +5%
CP
12
Catalys Pacific
Japan
$13.7M
GKIM
13
GW&K Investment Management
Massachusetts
$13.5M +$989K +95,858 +9%
CCM
14
Catalio Capital Management
New York
$13.3M +$4.71M +456,231 +68%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$12.8M +$196K +18,983 +2%
State Street
16
State Street
Massachusetts
$12.4M +$2.11M +204,167 +24%
MCM
17
Moore Capital Management
New York
$7.06M
Ameriprise
18
Ameriprise
Minnesota
$6.53M +$3.86M +373,739 +207%
PBM
19
Propel Bio Management
California
$6.51M -$3.82M -370,000 -40%
Citadel Advisors
20
Citadel Advisors
Florida
$5.99M +$5.25M +508,720 New
ACM
21
AIGH Capital Management
Maryland
$5.05M +$4.43M +429,000 New
SG
22
StepStone Group
California
$4.97M
SC
23
SummitTX Capital
Texas
$4.54M +$3.98M +385,968 New
Charles Schwab
24
Charles Schwab
California
$4.31M +$59.3K +5,744 +2%
Northern Trust
25
Northern Trust
Illinois
$4.21M -$18K -1,746 -0.5%

PHAT Hedge Fund Activity: Q3 2025 in Review

133 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Phathom Pharmaceuticals (PHAT) for Q3 2025, worth a combined $734M — up 33% from $551M a quarter earlier.

Buyers outnumbered sellers: 27 funds opened new PHAT positions and 11 closed out — a net gain of 16 holders — while 45 added to existing stakes and 28 trimmed.

The largest buyer was Millennium Management, adding an estimated $29.2M. The largest seller was Avidity Partners Management, cutting an estimated $7.83M.

  • 133 institutional investors held Phathom Pharmaceuticals (PHAT) as of Q3 2025, up from 117 in Q2 2025.
  • Funds reported $734M of Phathom Pharmaceuticals stock for Q3 2025, up 33% quarter-over-quarter.
  • 27 funds opened new Phathom Pharmaceuticals positions in Q3 2025 and 11 closed out, a net change of +16 holders.
  • The largest Phathom Pharmaceuticals buyer in Q3 2025 was Millennium Management, an estimated $29.2M added.
  • The largest Phathom Pharmaceuticals seller in Q3 2025 was Avidity Partners Management, an estimated $7.83M sold.

Based on aggregated 13F filings for Q3 2025.