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Phathom Pharmaceuticals

117 hedge funds and large institutions have $551M invested in Phathom Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 17 funds opening new positions, 43 increasing their positions, 37 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed

37% more capital invested

Capital invested by funds: $401M → $551M (+$149M)

27% more call options, than puts

Call options by funds: $15.4M | Put options by funds: $12.1M

16% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 37

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

9.71% less ownership

Funds ownership: 91.94%82.22% (-9.7%)

15% less funds holding

Funds holding: 137117 (-20)

53% less first-time investments, than exits

New positions opened: 17 | Existing positions closed: 36

Holders
117
Holders Change
-20
Holders Change %
-14.6%
% of All Funds
1.54%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
17
Increased
43
Reduced
37
Closed
36
Calls
$15.4M
Puts
$12.1M
Net Calls
+$3.22M
Net Calls Change
+$2.99M
Name Holding Trade Value Shares
Change
Change in
Stake
FLSM
1
Frazier Life Sciences Management
California
$120M +$13M +2,357,210 +23%
MVM
2
Medicxi Ventures Management
Jersey
$71.6M
Invesco
3
Invesco
Georgia
$39.7M +$2.71M +489,260 +13%
CG
4
Carlyle Group
District of Columbia
$33.5M
BlackRock
5
BlackRock
New York
$31.8M -$45.7K -8,255 -0.2%
Vanguard Group
6
Vanguard Group
Pennsylvania
$26.7M +$47.7K +8,624 +0.3%
Ensign Peak Advisors
7
Ensign Peak Advisors
Utah
$24.2M +$31.5K +5,688 +0.2%
Millennium Management
8
Millennium Management
New York
$21.6M +$9.56M +1,727,134 +330%
6CM
9
683 Capital Management
New York
$20.2M +$3.65M +660,000 +46%
NMC
10
NEA Management Company
Maryland
$18.8M
WA
11
Wasatch Advisors
Utah
$14M -$1.33M -239,732 -14%
CP
12
Catalys Pacific
Japan
$11.2M
Geode Capital Management
13
Geode Capital Management
Massachusetts
$10.3M +$296K +53,504 +5%
APM
14
Avidity Partners Management
Texas
$10.2M +$1.46M +264,500 +33%
GKIM
15
GW&K Investment Management
Massachusetts
$10.1M -$309K -55,836 -5%
PBM
16
Propel Bio Management
California
$8.85M -$1.17M -212,000 -19%
State Street
17
State Street
Massachusetts
$8.15M -$287K -51,930 -6%
CCM
18
Catalio Capital Management
New York
$6.45M +$3.72M +672,290 New
MCM
19
Moore Capital Management
New York
$5.75M +$3.32M +600,000 New
SAM
20
Simplify Asset Management
Nevada
$5.01M -$885K -160,000 -23%
Citigroup
21
Citigroup
New York
$4.96M -$75.3K -13,612 -3%
SG
22
StepStone Group
California
$4.05M
UBS Group
23
UBS Group
Switzerland
$4.02M -$1.59M -288,105 -41%
Charles Schwab
24
Charles Schwab
California
$3.45M +$67.1K +12,125 +3%
Northern Trust
25
Northern Trust
Illinois
$3.45M -$151K -27,299 -7%

PHAT Hedge Fund Activity: Q2 2025 in Review

117 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Phathom Pharmaceuticals (PHAT) for Q2 2025, worth a combined $551M — up 37% from $401M a quarter earlier.

Sellers outnumbered buyers: 36 funds closed out of PHAT and 17 opened new positions — a net loss of 19 holders — while 37 trimmed existing stakes and 43 added.

The largest buyer was Frazier Life Sciences Management, adding an estimated $13M. The largest seller was Jennison Associates, exiting entirely with an estimated $44.2M sold.

  • 117 institutional investors held Phathom Pharmaceuticals (PHAT) as of Q2 2025, down from 137 in Q1 2025.
  • Funds reported $551M of Phathom Pharmaceuticals stock for Q2 2025, up 37% quarter-over-quarter.
  • 17 funds opened new Phathom Pharmaceuticals positions in Q2 2025 and 36 closed out, a net change of -19 holders.
  • The largest Phathom Pharmaceuticals buyer in Q2 2025 was Frazier Life Sciences Management, an estimated $13M added.
  • The largest Phathom Pharmaceuticals seller in Q2 2025 was Jennison Associates, an estimated $44.2M sold.

Based on aggregated 13F filings for Q2 2025.