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Phathom Pharmaceuticals

117 hedge funds and large institutions have $551M invested in Phathom Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 17 funds opening new positions, 43 increasing their positions, 37 reducing their positions, and 36 closing their positions.

New
Increased
Maintained
Reduced
Closed

37% more capital invested

Capital invested by funds: $401M → $551M (+$149M)

27% more call options, than puts

Call options by funds: $15.4M | Put options by funds: $12.1M

16% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 37

0% more funds holding in top 10

Funds holding in top 10: 66 (0)

9.71% less ownership

Funds ownership: 91.94%82.22% (-9.7%)

15% less funds holding

Funds holding: 137117 (-20)

53% less first-time investments, than exits

New positions opened: 17 | Existing positions closed: 36

Holders
117
Holders Change
-20
Holders Change %
-14.6%
% of All Funds
1.54%
Holding in Top 10
6
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.08%
New
17
Increased
43
Reduced
37
Closed
36
Calls
$15.4M
Puts
$12.1M
Net Calls
+$3.22M
Net Calls Change
+$2.99M
Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Investments
126
Two Sigma Investments
New York
-$610K -97,327 Closed
Swiss National Bank
127
Swiss National Bank
Switzerland
-$460K -73,300 Closed
Los Angeles Capital Management
128
Los Angeles Capital Management
California
-$377K -60,056 Closed
HF
129
HRT Financial
New York
-$208K -33,297 Closed
EGM
130
Engineers Gate Manager
New York
-$167K -26,623 Closed
SPA
131
Sherbrooke Park Advisers
New York
-$165K -26,307 Closed
KeyBank National Association
132
KeyBank National Association
Ohio
-$160K -25,512 Closed
Simplex Trading
133
Simplex Trading
Illinois
-$124K -22,474 Closed
CF
134
Corebridge Financial
Texas
-$122K -19,532 Closed
CC
135
Corton Capital
Ontario, Canada
-$115K -18,384 Closed
Zurich Cantonal Bank
136
Zurich Cantonal Bank
Switzerland
-$98.5K -15,710 Closed
ASRS
137
Arizona State Retirement System
Arizona
-$67.5K -10,768 Closed
AI
138
Atom Investors
Texas
-$65.2K -10,394 Closed
Teacher Retirement System of Texas
139
Teacher Retirement System of Texas
Texas
-$63.5K -10,122 Closed
KK
140
KLP Kapitalforvaltning
Norway
-$57.1K -9,100 Closed
Canada Life
141
Canada Life
Manitoba, Canada
-$18K -2,839 Closed
Group One Trading
142
Group One Trading
Illinois
-$13.3K -2,404 Closed
Public Employees Retirement Association of Colorado
143
Public Employees Retirement Association of Colorado
Colorado
-$5K -840 Closed
S
144
SignatureFD
Georgia
-$2.9K -463 Closed
VCM
145
Versant Capital Management
Arizona
-$1.24K -197 Closed
CIAM
146
Caitong International Asset Management
Hong Kong
-$709 -113 Closed
CCM
147
Coldstream Capital Management
Washington
-$684 -109 Closed
PFBT
148
Parkside Financial Bank & Trust
Missouri
-$533 -85 Closed
QCG
149
Quadrant Capital Group
Ohio
-$527 -84 Closed
Amundi
150
Amundi
France
-$210 -42 Closed

PHAT Hedge Fund Activity: Q2 2025 in Review

117 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Phathom Pharmaceuticals (PHAT) for Q2 2025, worth a combined $551M — up 37% from $401M a quarter earlier.

Sellers outnumbered buyers: 36 funds closed out of PHAT and 17 opened new positions — a net loss of 19 holders — while 37 trimmed existing stakes and 43 added.

The largest buyer was Frazier Life Sciences Management, adding an estimated $13M. The largest seller was Jennison Associates, exiting entirely with an estimated $44.2M sold.

  • 117 institutional investors held Phathom Pharmaceuticals (PHAT) as of Q2 2025, down from 137 in Q1 2025.
  • Funds reported $551M of Phathom Pharmaceuticals stock for Q2 2025, up 37% quarter-over-quarter.
  • 17 funds opened new Phathom Pharmaceuticals positions in Q2 2025 and 36 closed out, a net change of -19 holders.
  • The largest Phathom Pharmaceuticals buyer in Q2 2025 was Frazier Life Sciences Management, an estimated $13M added.
  • The largest Phathom Pharmaceuticals seller in Q2 2025 was Jennison Associates, an estimated $44.2M sold.

Based on aggregated 13F filings for Q2 2025.