Palisade Bio
PALI
86 hedge funds and large institutions have $319M invested in Palisade Bio in 2025 Q4 according to their latest regulatory filings, with 75 funds opening new positions, 7 increasing their positions, 1 reducing their positions, and 1 closing their positions.
310,512% more capital invested
Capital invested by funds: $103K → $319M (+$319M)
7,400% more first-time investments, than exits
New positions opened: 75 | Existing positions closed: 1
617% more funds holding
Funds holding: 12 → 86 (+74)
600% more repeat investments, than reductions
Existing positions increased: 7 | Existing positions reduced: 1
89.88% more ownership
Funds ownership: 1.31% → 91.19% (+90%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
PA
Perceptive Advisors
New York
|
+$23.2M |
| 2 |
CC
Commodore Capital
New York
|
+$22M |
| 3 |
Janus Henderson Group
London,
|
+$20.3M |
| 4 |
Point72 Asset Management
Stamford,
Connecticut
|
+$20.2M |
| 5 |
OCA
Octagon Capital Advisors
New York
|
+$18.4M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
TSS
Two Sigma Securities
New York
|
-$25.3K |
| 2 |
TRCT
Tower Research Capital (TRC)
New York
|
-$8.4K |
PALI Hedge Fund Activity: Q4 2025 in Review
86 institutional investors reported a position in Palisade Bio (PALI) for Q4 2025, worth a combined $319M — up 310,512% from $103K a quarter earlier.
Buyers outnumbered sellers: 75 funds opened new PALI positions and 1 closed out — a net gain of 74 holders — while 7 added to existing stakes and 1 trimmed.
The largest buyer was Perceptive Advisors, opening a new position worth an estimated $23.2M. The largest seller was Two Sigma Securities, exiting entirely with an estimated $25.3K sold.
- 86 institutional investors held Palisade Bio (PALI) as of Q4 2025, up from 12 in Q3 2025.
- Funds reported $319M of Palisade Bio stock for Q4 2025, up 310,512% quarter-over-quarter.
- 75 funds opened new Palisade Bio positions in Q4 2025 and 1 closed out, a net change of +74 holders.
- The largest Palisade Bio buyer in Q4 2025 was Perceptive Advisors, an estimated $23.2M added.
- The largest Palisade Bio seller in Q4 2025 was Two Sigma Securities, an estimated $25.3K sold.
Based on aggregated 13F filings for Q4 2025.