|
1
|
BVF Inc
San Francisco,
California
|
$10.4M
|
+$4.19M
|
+900,000
|
+25%
|
|
|
2
|
|
$7.88M
|
+$3.04M
|
+652,042
|
+24%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$7.17M
|
+$2.37M
|
+509,417
|
+20%
|
|
|
4
|
|
$5.78M
|
–
|
–
|
–
|
|
|
5
|
Vivo Capital
Palo Alto,
California
|
$2.89M
|
–
|
–
|
–
|
|
|
6
|
UBS Group
Zurich,
Switzerland
|
$2.38M
|
+$2.7M
|
+579,322
|
+129%
|
|
|
7
|
Baker Bros. Advisors
New York
|
$2.21M
|
+$1.7M
|
+364,929
|
+62%
|
|
|
8
|
|
$1.91M
|
+$975K
|
+209,168
|
+34%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$1.71M
|
+$56.9K
|
+12,208
|
+2%
|
|
|
10
|
Renaissance Technologies
New York
|
$1.64M
|
+$3.31M
|
+710,507
|
New
|
|
|
11
|
|
$1.43M
|
+$120K
|
+25,735
|
+4%
|
|
|
12
|
Two Sigma Advisers
New York
|
$1.37M
|
+$1.98M
|
+425,200
|
+253%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$1.32M
|
+$8.46K
|
+1,816
|
+0.3%
|
|
|
14
|
Wells Fargo
San Francisco,
California
|
$1.27M
|
+$77.7K
|
+16,673
|
+3%
|
|
|
15
|
Nuveen
Charlotte,
North Carolina
|
$1.17M
|
+$22.8K
|
+4,897
|
+3%
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$1.16M
|
+$79.2K
|
+16,990
|
+4%
|
|
|
17
|
|
$1.1M
|
+$1.97M
|
+423,032
|
+821%
|
|
|
18
|
Platinum Investment Management
Sydney Australia 2000,
Australia
|
$917K
|
+$762K
|
+163,457
|
+70%
|
|
|
19
|
Tekla Capital Management
Boston,
Massachusetts
|
$861K
|
–
|
–
|
–
|
|
|
20
|
Acadian Asset Management
Boston,
Massachusetts
|
$815K
|
+$1.64M
|
+352,658
|
New
|
|
|
21
|
Two Sigma Investments
New York
|
$799K
|
+$119K
|
+25,441
|
+8%
|
|
|
22
|
RA Capital Management
Boston,
Massachusetts
|
$658K
|
–
|
–
|
–
|
|
|
23
|
Millennium Management
New York
|
$587K
|
+$1.01M
|
+217,739
|
+600%
|
|
|
24
|
Connor, Clark & Lunn Investment Management (CC&L)
Vancouver,
British Columbia, Canada
|
$536K
|
+$383K
|
+82,070
|
+55%
|
|
|
25
|
|
$490K
|
+$990K
|
+212,393
|
New
|
|
