|
1
|
|
$21.5M
|
+$11.3M
|
+2,424,104
|
+495%
|
|
|
2
|
Consonance Capital Management
New York
|
$18.9M
|
-$46.8K
|
-10,000
|
-0.4%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$17.6M
|
+$5.17M
|
+1,106,147
|
+86%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$15.6M
|
+$1.98M
|
+422,661
|
+25%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$13.1M
|
-$1.42M
|
-303,685
|
-15%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$5.42M
|
+$3.44M
|
+735,956
|
New
|
|
|
7
|
|
$5.23M
|
-$496K
|
-106,122
|
-13%
|
|
|
8
|
|
$4.98M
|
+$3.16M
|
+675,900
|
New
|
|
|
9
|
Renaissance Technologies
New York
|
$4.6M
|
-$1.07M
|
-228,734
|
-27%
|
|
|
10
|
Geode Capital Management
Boston,
Massachusetts
|
$4.33M
|
+$1.37M
|
+293,721
|
+100%
|
|
|
11
|
|
$4.01M
|
-$1.33M
|
-284,132
|
-34%
|
|
|
12
|
Millennium Management
New York
|
$3.85M
|
+$578K
|
+123,638
|
+31%
|
|
|
13
|
Wells Fargo
San Francisco,
California
|
$3.84M
|
+$143K
|
+30,614
|
+6%
|
|
|
14
|
Assenagon Asset Management
Senningerberg,
Luxembourg
|
$3.76M
|
+$1.83M
|
+390,242
|
+325%
|
|
|
15
|
Northern Trust
Chicago,
Illinois
|
$3.73M
|
+$2.04M
|
+435,638
|
+624%
|
|
|
16
|
Baker Bros. Advisors
New York
|
$3.38M
|
+$1.82M
|
+388,782
|
+560%
|
|
|
17
|
Tekla Capital Management
Boston,
Massachusetts
|
$2.75M
|
–
|
–
|
–
|
|
|
18
|
Platinum Investment Management
Sydney Australia 2000,
Australia
|
$2.22M
|
-$380K
|
-81,346
|
-21%
|
|
|
19
|
RA Capital Management
Boston,
Massachusetts
|
$2.1M
|
+$1.33M
|
+285,000
|
New
|
|
|
20
|
Nuveen
Charlotte,
North Carolina
|
$1.5M
|
+$951K
|
+203,275
|
New
|
|
|
21
|
Connor, Clark & Lunn Investment Management (CC&L)
Vancouver,
British Columbia, Canada
|
$1.4M
|
+$147K
|
+31,380
|
+20%
|
|
|
22
|
EAM Investors
Solana Beach,
California
|
$1.36M
|
–
|
–
|
–
|
|
|
23
|
|
$1.11M
|
+$135K
|
+28,826
|
+24%
|
|
|
24
|
UBS Group
Zurich,
Switzerland
|
$980K
|
-$351K
|
-74,974
|
-36%
|
|
|
25
|
Fairpointe Capital
Chicago,
Illinois
|
$934K
|
-$70.2K
|
-15,000
|
-11%
|
|
