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ORKA

Oruka Therapeutics

143 hedge funds and large institutions have $1.6B invested in Oruka Therapeutics in 2025 Q4 according to their latest regulatory filings, with 46 funds opening new positions, 54 increasing their positions, 16 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

475% more first-time investments, than exits

New positions opened: 46 | Existing positions closed: 8

238% more repeat investments, than reductions

Existing positions increased: 54 | Existing positions reduced: 16

83% more capital invested

Capital invested by funds: $876M → $1.6B (+$726M)

40% more funds holding in top 10

Funds holding in top 10: 57 (+2)

36% more funds holding

Funds holding: 105143 (+38)

13% more call options, than puts

Call options by funds: $527K | Put options by funds: $467K

12.47% less ownership

Funds ownership: 121.65%109.18% (-12%)

Holders
143
Holders Change
+38
Holders Change %
+36.19%
% of All Funds
1.74%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.09%
New
46
Increased
54
Reduced
16
Closed
8
Calls
$527K
Puts
$467K
Net Calls
+$60K
Net Calls Change
+$2.59M
Name Holding Trade Value Shares
Change
Change in
Stake
SAM
51
Secure Asset Management
Michigan
$2.48M +$2.28M +81,664 New
TD Asset Management
52
TD Asset Management
Ontario, Canada
$2.42M +$948K +34,020 +74%
D.E. Shaw & Co
53
D.E. Shaw & Co
New York
$2.32M -$529K -19,002 -20%
Aberdeen Group
54
Aberdeen Group
United Kingdom
$2.29M
BGI
55
B Group Inc
Texas
$2.27M
PAI
56
Palo Alto Investors
California
$1.82M
Manulife (Manufacturers Life Insurance)
57
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$1.8M +$263K +9,450 +18%
Millennium Management
58
Millennium Management
New York
$1.78M +$1.64M +58,723 New
American Century Companies
59
American Century Companies
Missouri
$1.73M +$640K +22,969 +67%
KCM
60
Kennedy Capital Management
Missouri
$1.48M +$11.7K +420 +0.9%
Wells Fargo
61
Wells Fargo
California
$1.31M +$624K +22,405 +107%
Swiss National Bank
62
Swiss National Bank
Switzerland
$1.3M +$1.2M +43,000 New
VOYA Investment Management
63
VOYA Investment Management
Georgia
$1.29M +$1.18M +42,503 New
RhumbLine Advisers
64
RhumbLine Advisers
Massachusetts
$1.24M +$298K +10,690 +35%
AA
65
ALPS Advisors
Colorado
$1.2M +$1.11M +39,751 New
Rafferty Asset Management
66
Rafferty Asset Management
New York
$1.17M +$716K +25,698 +201%
AllianceBernstein
67
AllianceBernstein
Tennessee
$1.15M +$1.05M +37,800 New
Verition Fund Management
68
Verition Fund Management
Connecticut
$1.08M +$995K +35,710 New
FEG
69
Financial Enhancement Group
Indiana
$1.08M -$42.5K -1,526 -5%
Two Sigma Investments
70
Two Sigma Investments
New York
$866K
Schroder Investment Management Group
71
Schroder Investment Management Group
United Kingdom
$850K
Squarepoint
72
Squarepoint
New York
$839K +$771K +27,671 New
VCM
73
Voleon Capital Management
California
$714K +$656K +23,548 New
State of Wisconsin Investment Board
74
State of Wisconsin Investment Board
Wisconsin
$696K +$640K +22,968 New
California State Teachers Retirement System (CalSTRS)
75
California State Teachers Retirement System (CalSTRS)
California
$656K +$556K +19,960 +1,176%