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ORKA

Oruka Therapeutics

143 hedge funds and large institutions have $1.6B invested in Oruka Therapeutics in 2025 Q4 according to their latest regulatory filings, with 46 funds opening new positions, 54 increasing their positions, 16 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

475% more first-time investments, than exits

New positions opened: 46 | Existing positions closed: 8

238% more repeat investments, than reductions

Existing positions increased: 54 | Existing positions reduced: 16

83% more capital invested

Capital invested by funds: $876M → $1.6B (+$726M)

40% more funds holding in top 10

Funds holding in top 10: 57 (+2)

36% more funds holding

Funds holding: 105143 (+38)

13% more call options, than puts

Call options by funds: $527K | Put options by funds: $467K

12.47% less ownership

Funds ownership: 121.65%109.18% (-12%)

Holders
143
Holders Change
+38
Holders Change %
+36.19%
% of All Funds
1.74%
Holding in Top 10
7
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+40%
% of All Funds
0.09%
New
46
Increased
54
Reduced
16
Closed
8
Calls
$527K
Puts
$467K
Net Calls
+$60K
Net Calls Change
+$2.59M
Name Holding Trade Value Shares
Change
Change in
Stake
Fidelity Investments
1
Fidelity Investments
Massachusetts
$220M +$105K +3,763 +0.1%
VA
2
VR Adviser
New York
$126M
FFM
3
Fairmount Funds Management
Pennsylvania
$112M
BlackRock
4
BlackRock
New York
$107M +$37.2M +1,334,864 +61%
Viking Global Investors
5
Viking Global Investors
Connecticut
$80.8M
Vanguard Group
6
Vanguard Group
Pennsylvania
$74.4M +$18.9M +676,865 +38%
DTC
7
Deep Track Capital
Connecticut
$65.5M -$13.7M -493,271 -19%
RI
8
RTW Investments
New York
$62.4M +$3.13M +112,499 +6%
CC
9
Commodore Capital
New York
$53.1M
PBA
10
Paradigm Biocapital Advisors
New York
$51.8M +$47.7M +1,710,316 New
RCP
11
Remedium Capital Partners
Florida
$47.1M +$43.3M +1,552,414 New
PA
12
Perceptive Advisors
New York
$44.8M +$5.81M +208,480 +16%
State Street
13
State Street
Massachusetts
$41.9M +$20.4M +731,819 +112%
ACA
14
Avoro Capital Advisors
New York
$40.4M
Blackstone Inc
15
Blackstone Inc
New York
$35.3M +$8.78M +315,008 +37%
PCH
16
Polar Capital Holdings
United Kingdom
$29.7M -$1.51M -54,019 -5%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$28.6M +$7.04M +252,535 +37%
Franklin Resources
18
Franklin Resources
California
$28.4M -$3.55M -127,361 -12%
AAA
19
Affinity Asset Advisors
New York
$24.3M -$4.37M -156,838 -16%
Mercer Global Advisors
20
Mercer Global Advisors
Colorado
$22.6M -$2.98M -107,134 -13%
Citadel Advisors
21
Citadel Advisors
Florida
$22M +$11.4M +409,232 +129%
APM
22
Avidity Partners Management
Texas
$20M
T. Rowe Price Associates
23
T. Rowe Price Associates
Maryland
$19.7M +$628K +22,540 +4%
Point72 Asset Management
24
Point72 Asset Management
Connecticut
$18.2M -$12.2M -437,002 -42%
WP
25
Woodline Partners
California
$17.4M +$6.21K +223 +0%