|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$155M
|
+$119M
|
+5,363,753
|
+107%
|
|
|
2
|
Paradigm Biocapital Advisors
New York
|
$120M
|
+$10.6M
|
+476,404
|
+6%
|
|
|
3
|
Bain Capital Life Sciences Investors
Boston,
Massachusetts
|
$111M
|
-$23M
|
-1,035,403
|
-12%
|
|
|
4
|
Janus Henderson Group
London,
|
$106M
|
+$8.87M
|
+398,294
|
+6%
|
|
|
5
|
|
$84.3M
|
+$1.98M
|
+88,875
|
+2%
|
|
|
6
|
BVF Inc
San Francisco,
California
|
$79M
|
–
|
–
|
–
|
|
|
7
|
Siren LLC
Greenwich,
Connecticut
|
$70.9M
|
+$32.4M
|
+1,456,249
|
+44%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$58.7M
|
+$45.7M
|
+2,053,432
|
+109%
|
|
|
9
|
Cormorant Asset Management
Boston,
Massachusetts
|
$58.1M
|
+$25.6M
|
+1,150,000
|
+42%
|
|
|
10
|
Logos Global Management
San Francisco,
California
|
$47.8M
|
–
|
–
|
–
|
|
|
11
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$46M
|
+$68.6M
|
+3,083,517
|
New
|
|
|
12
|
RA Capital Management
Boston,
Massachusetts
|
$38.8M
|
–
|
–
|
–
|
|
|
13
|
Jennison Associates
New York
|
$27.2M
|
+$19.1M
|
+858,126
|
+89%
|
|
|
14
|
Polar Capital Holdings
London,
United Kingdom
|
$23.9M
|
+$4.95M
|
+222,520
|
+16%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$23M
|
+$6.39M
|
+286,976
|
+23%
|
|
|
16
|
Defilade Capital Management
Emeryville,
California
|
$22.4M
|
+$6.01M
|
+269,902
|
+22%
|
|
|
17
|
Woodline Partners
San Francisco,
California
|
$22.1M
|
+$2.23K
|
+100
|
+0%
|
|
|
18
|
Lightspeed Management Company
Menlo Park,
California
|
$20.2M
|
-$12.8M
|
-575,595
|
-30%
|
|
|
19
|
Franklin Resources
San Mateo,
California
|
$18.2M
|
-$28M
|
-1,257,708
|
-51%
|
|
|
20
|
|
$18.1M
|
+$12.2M
|
+549,887
|
+83%
|
|
|
21
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$17.6M
|
+$1.93M
|
+86,801
|
+8%
|
|
|
22
|
Two Sigma Investments
New York
|
$17.4M
|
+$17.3M
|
+775,763
|
+197%
|
|
|
23
|
Dimensional Fund Advisors
Austin,
Texas
|
$16.1M
|
+$2.76M
|
+123,790
|
+13%
|
|
|
24
|
|
$15.6M
|
+$5.07M
|
+227,700
|
+28%
|
|
|
25
|
Duquesne Family Office
New York
|
$14.7M
|
+$22M
|
+986,827
|
New
|
|
