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Olema Pharmaceuticals
OLMA

200 hedge funds and large institutions have $2.27B invested in Olema Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 87 funds opening new positions, 55 increasing their positions, 39 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

625% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 12

450% more funds holding in top 10

Funds holding in top 10: 2 → 11 (+9)

239% more capital invested

Capital invested by funds: $668M → $2.27B (+$1.6B)

76% more call options, than puts

Call options by funds: $30.8M | Put options by funds: $17.5M

59% more funds holding

Funds holding: 126 → 200 (+74)

41% more repeat investments, than reductions

Existing positions increased: 55 | Existing positions reduced: 39

32.66% more ownership

Funds ownership: 99.49% → 132.15% (+33%)

Holders
200
Holders Change
+74
Holders Change %
+58.73%
% of All Funds
2.43%
Holding in Top 10
11
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+450%
% of All Funds
0.13%
New
87
Increased
55
Reduced
39
Closed
12
Calls
$30.8M
Puts
$17.5M
Net Calls
+$13.3M
Net Calls Change
+$7.65M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$88.9M
2
SL
Siren LLC
Connecticut
+$58.7M
3
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$55.6M
4
CAM
Cormorant Asset Management
Massachusetts
+$48.9M
5
RCM
RA Capital Management
Massachusetts
+$46.3M

Top Sellers

1
DTC
Deep Track Capital
Connecticut
-$34M
2
Pictet Asset Management
Pictet Asset Management
Switzerland
-$20.2M
3
Ameriprise
Ameriprise
Minnesota
-$16.8M
4
UBS Group
UBS Group
Switzerland
-$16M
5
Morgan Stanley
Morgan Stanley
New York
-$15.8M
Name Holding Trade Value Shares
Change 		Change in
Stake
Carson Wealth (CWM LLC)
151
Carson Wealth (CWM LLC)
Nebraska
$157K -$516 -29 -0.5%
Simplex Trading
152
Simplex Trading
Illinois
$133K -$362K -20,371 -79%
AIP
153
Ameritas Investment Partners
Nebraska
$124K – – –
Russell Investments Group
154
Russell Investments Group
United Kingdom
$118K -$11.8K -664 -12%
SOW
155
State of Wyoming
Wyoming
$117K -$10.7K -599 -11%
BG
156
Bellevue Group
Switzerland
$97.5K +$69.4K +3,902 New
Mirae Asset Global Investments
157
Mirae Asset Global Investments
South Korea
$95.5K +$20.8K +1,169 +44%
Nisa Investment Advisors
158
Nisa Investment Advisors
Missouri
$94.1K +$8.49K +477 +15%
California State Teachers Retirement System (CalSTRS)
159
California State Teachers Retirement System (CalSTRS)
California
$91.7K -$1.1K -62 -2%
FISPB
160
Fideuram - Intesa Sanpaolo Private Banking
$87.5K +$62.3K +3,500 New
SCM
161
Sterling Capital Management
North Carolina
$86K -$11.9K -668 -16%
QL
162
Quarry LP
New York
$75K -$280K -15,750 -84%
JFG
163
Jefferies Financial Group
New York
$75K +$53.4K +3,000 New
FDCDDQ
164
Federation des caisses Desjardins du Quebec
Quebec, Canada
$50K – – –
AB
165
Amalgamated Bank
New York
$47K +$8.19K +460 +33%
TM
166
Torren Management
California
$44K +$31.3K +1,759 New
A
167
AlphaQuest
New York
$42.3K +$14.1K +792 +88%
GFM
168
GF Fund Management
China
$38.6K +$1.23K +69 +5%
EWA
169
EverSource Wealth Advisors
Alabama
$31.1K +$21.9K +1,232 +9,477%
Jones Financial Companies
170
Jones Financial Companies
Missouri
$29.8K +$21.2K +1,191 New
VCM
171
Versant Capital Management
Arizona
$29.4K -$4.36K -245 -17%
TC
172
Truvestments Capital
Florida
$20.9K – – –
GI
173
GAMMA Investing
California
$18.1K +$8.76K +492 +213%
WWM
174
Wolff Wiese Magana
California
$15K – – –
AAP
175
Arax Advisory Partners
Colorado
$14.1K +$9.95K +559 +11,180%
5 6
7
8 9

OLMA Hedge Fund Activity: Q4 2025 in Review

200 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Olema Pharmaceuticals (OLMA) for Q4 2025, worth a combined $2.27B — up 239% from $668M a quarter earlier.

Buyers outnumbered sellers: 87 funds opened new OLMA positions and 12 closed out — a net gain of 75 holders — while 55 added to existing stakes and 39 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $88.9M. The largest seller was Deep Track Capital, exiting entirely with an estimated $34M sold.

  • 200 institutional investors held Olema Pharmaceuticals (OLMA) as of Q4 2025, up from 126 in Q3 2025.
  • Funds reported $2.27B of Olema Pharmaceuticals stock for Q4 2025, up 239% quarter-over-quarter.
  • 87 funds opened new Olema Pharmaceuticals positions in Q4 2025 and 12 closed out, a net change of +75 holders.
  • The largest Olema Pharmaceuticals buyer in Q4 2025 was Fidelity Investments, an estimated $88.9M added.
  • The largest Olema Pharmaceuticals seller in Q4 2025 was Deep Track Capital, an estimated $34M sold.

Based on aggregated 13F filings for Q4 2025.