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Olema Pharmaceuticals
OLMA

200 hedge funds and large institutions have $2.27B invested in Olema Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 87 funds opening new positions, 55 increasing their positions, 39 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

625% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 12

450% more funds holding in top 10

Funds holding in top 10: 2 → 11 (+9)

239% more capital invested

Capital invested by funds: $668M → $2.27B (+$1.6B)

76% more call options, than puts

Call options by funds: $30.8M | Put options by funds: $17.5M

59% more funds holding

Funds holding: 126 → 200 (+74)

41% more repeat investments, than reductions

Existing positions increased: 55 | Existing positions reduced: 39

32.66% more ownership

Funds ownership: 99.49% → 132.15% (+33%)

Holders
200
Holders Change
+74
Holders Change %
+58.73%
% of All Funds
2.43%
Holding in Top 10
11
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+450%
% of All Funds
0.13%
New
87
Increased
55
Reduced
39
Closed
12
Calls
$30.8M
Puts
$17.5M
Net Calls
+$13.3M
Net Calls Change
+$7.65M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$88.9M
2
SL
Siren LLC
Connecticut
+$58.7M
3
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$55.6M
4
CAM
Cormorant Asset Management
Massachusetts
+$48.9M
5
RCM
RA Capital Management
Massachusetts
+$46.3M

Top Sellers

1
DTC
Deep Track Capital
Connecticut
-$34M
2
Pictet Asset Management
Pictet Asset Management
Switzerland
-$20.2M
3
Ameriprise
Ameriprise
Minnesota
-$16.8M
4
UBS Group
UBS Group
Switzerland
-$16M
5
Morgan Stanley
Morgan Stanley
New York
-$15.8M
Name Holding Trade Value Shares
Change 		Change in
Stake
PFSRSONJ
126
Police & Firemen's Retirement System of New Jersey
New Jersey
$416K – – –
ACM
127
Aquatic Capital Management
Illinois
$383K +$273K +15,314 New
IC
128
Inscription Capital
Texas
$382K +$272K +15,273 New
Polen Capital Management
129
Polen Capital Management
Florida
$380K +$271K +15,206 New
ProShare Advisors
130
ProShare Advisors
Maryland
$359K +$31K +1,740 +14%
Los Angeles Capital Management
131
Los Angeles Capital Management
California
$334K +$678K +38,078 New
CUAMC
132
China Universal Asset Management Company
China
$325K +$17.6K +987 +8%
LCM
133
Legato Capital Management
California
$289K +$206K +11,554 New
Susquehanna International Group
134
Susquehanna International Group
Pennsylvania
$281K -$1.8M -101,053 -90%
Cetera Investment Advisers
135
Cetera Investment Advisers
Illinois
$263K +$187K +10,500 New
SO
136
STRS Ohio
Ohio
$263K +$187K +10,500 New
BNP Paribas Financial Markets
137
BNP Paribas Financial Markets
France
$259K -$5.15M -289,257 -97%
BAM
138
Blueshift Asset Management
New Jersey
$256K +$182K +10,237 New
WANY
139
Wealthspire Advisors (New York)
New York
$254K +$181K +10,172 New
EWA
140
EP Wealth Advisors
California
$250K +$178K +10,009 New
CCM
141
Conway Capital Management
California
$250K – – –
D.E. Shaw & Co
142
D.E. Shaw & Co
New York
$249K +$177K +9,954 New
TRCT
143
Tower Research Capital (TRC)
New York
$248K +$132K +7,413 +294%
OC
144
Oppenheimer & Co
New York
$238K +$169K +9,500 New
PAP
145
Persistent Asset Partners
Hong Kong
$227K +$161K +9,069 New
State Board of Administration of Florida Retirement System
146
State Board of Administration of Florida Retirement System
Florida
$222K +$158K +8,880 New
SEI Investments
147
SEI Investments
Pennsylvania
$206K +$147K +8,259 New
VIA
148
Virtus Investment Advisers
Connecticut
$201K -$355K -19,977 -71%
QT
149
Quantbot Technologies
New York
$201K +$143K +8,046 New
Royal Bank of Canada
150
Royal Bank of Canada
Ontario, Canada
$167K -$2.52M -141,637 -95%
4 5
6
7 8

OLMA Hedge Fund Activity: Q4 2025 in Review

200 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Olema Pharmaceuticals (OLMA) for Q4 2025, worth a combined $2.27B — up 239% from $668M a quarter earlier.

Buyers outnumbered sellers: 87 funds opened new OLMA positions and 12 closed out — a net gain of 75 holders — while 55 added to existing stakes and 39 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $88.9M. The largest seller was Deep Track Capital, exiting entirely with an estimated $34M sold.

  • 200 institutional investors held Olema Pharmaceuticals (OLMA) as of Q4 2025, up from 126 in Q3 2025.
  • Funds reported $2.27B of Olema Pharmaceuticals stock for Q4 2025, up 239% quarter-over-quarter.
  • 87 funds opened new Olema Pharmaceuticals positions in Q4 2025 and 12 closed out, a net change of +75 holders.
  • The largest Olema Pharmaceuticals buyer in Q4 2025 was Fidelity Investments, an estimated $88.9M added.
  • The largest Olema Pharmaceuticals seller in Q4 2025 was Deep Track Capital, an estimated $34M sold.

Based on aggregated 13F filings for Q4 2025.