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Olema Pharmaceuticals
OLMA

200 hedge funds and large institutions have $2.27B invested in Olema Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 87 funds opening new positions, 55 increasing their positions, 39 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

625% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 12

450% more funds holding in top 10

Funds holding in top 10: 2 → 11 (+9)

239% more capital invested

Capital invested by funds: $668M → $2.27B (+$1.6B)

76% more call options, than puts

Call options by funds: $30.8M | Put options by funds: $17.5M

59% more funds holding

Funds holding: 126 → 200 (+74)

41% more repeat investments, than reductions

Existing positions increased: 55 | Existing positions reduced: 39

32.66% more ownership

Funds ownership: 99.49% → 132.15% (+33%)

Holders
200
Holders Change
+74
Holders Change %
+58.73%
% of All Funds
2.43%
Holding in Top 10
11
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+450%
% of All Funds
0.13%
New
87
Increased
55
Reduced
39
Closed
12
Calls
$30.8M
Puts
$17.5M
Net Calls
+$13.3M
Net Calls Change
+$7.65M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$88.9M
2
SL
Siren LLC
Connecticut
+$58.7M
3
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$55.6M
4
CAM
Cormorant Asset Management
Massachusetts
+$48.9M
5
RCM
RA Capital Management
Massachusetts
+$46.3M

Top Sellers

1
DTC
Deep Track Capital
Connecticut
-$34M
2
Pictet Asset Management
Pictet Asset Management
Switzerland
-$20.2M
3
Ameriprise
Ameriprise
Minnesota
-$16.8M
4
UBS Group
UBS Group
Switzerland
-$16M
5
Morgan Stanley
Morgan Stanley
New York
-$15.8M
Name Holding Trade Value Shares
Change 		Change in
Stake
HF
101
HRT Financial
New York
$1.01M +$427K +23,975 +147%
YIH
102
Y-Intercept (HK)
Hong Kong
$930K +$662K +37,199 New
CCIA
103
Campbell & Co Investment Adviser
Maryland
$889K +$116K +6,508 +22%
State of Wisconsin Investment Board
104
State of Wisconsin Investment Board
Wisconsin
$874K +$622K +34,940 New
MIM
105
MetLife Investment Management
New Jersey
$838K -$73.3K -4,120 -11%
Verition Fund Management
106
Verition Fund Management
Connecticut
$835K +$594K +33,382 New
Mirae Asset Global ETFs Holdings
107
Mirae Asset Global ETFs Holdings
Hong Kong
$757K +$52.2K +2,934 +11%
JG
108
Jain Global
New York
$754K +$537K +30,160 New
II
109
Ishara Investments
California
$750K +$534K +30,000 New
New York State Common Retirement Fund
110
New York State Common Retirement Fund
New York
$706K +$345K +19,366 +218%
PP
111
PDT Partners
New York
$684K +$215K +12,067 +79%
EGM
112
Engineers Gate Manager
New York
$655K +$466K +26,207 New
VOYA Investment Management
113
VOYA Investment Management
Georgia
$650K +$265K +14,909 +135%
IIM
114
INTECH Investment Management
Florida
$630K +$207K +11,631 +86%
Renaissance Technologies
115
Renaissance Technologies
New York
$627K -$1.16M -65,033 -72%
EFMC
116
Empire Financial Management Company
New York
$625K +$445K +25,000 New
AC
117
AXQ Capital
New Jersey
$533K +$379K +21,323 New
SC
118
Shay Capital
New York
$525K +$374K +21,000 New
Legal & General Group
119
Legal & General Group
United Kingdom
$512K +$268K +15,068 +278%
HA
120
Huntleigh Advisors
Missouri
$503K +$358K +20,130 New
Acadian Asset Management
121
Acadian Asset Management
Massachusetts
$477K +$340K +19,088 New
PR
122
PSP Research
Pennsylvania
$477K +$339K +19,063 New
SRL
123
Scientech Research LLC
New Jersey
$437K +$311K +17,474 New
PA
124
Profund Advisors
Maryland
$435K +$309K +17,381 New
ET
125
Entropy Technologies
New York
$433K +$308K +17,304 New
3 4
5
6 7

OLMA Hedge Fund Activity: Q4 2025 in Review

200 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Olema Pharmaceuticals (OLMA) for Q4 2025, worth a combined $2.27B — up 239% from $668M a quarter earlier.

Buyers outnumbered sellers: 87 funds opened new OLMA positions and 12 closed out — a net gain of 75 holders — while 55 added to existing stakes and 39 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $88.9M. The largest seller was Deep Track Capital, exiting entirely with an estimated $34M sold.

  • 200 institutional investors held Olema Pharmaceuticals (OLMA) as of Q4 2025, up from 126 in Q3 2025.
  • Funds reported $2.27B of Olema Pharmaceuticals stock for Q4 2025, up 239% quarter-over-quarter.
  • 87 funds opened new Olema Pharmaceuticals positions in Q4 2025 and 12 closed out, a net change of +75 holders.
  • The largest Olema Pharmaceuticals buyer in Q4 2025 was Fidelity Investments, an estimated $88.9M added.
  • The largest Olema Pharmaceuticals seller in Q4 2025 was Deep Track Capital, an estimated $34M sold.

Based on aggregated 13F filings for Q4 2025.