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Olema Pharmaceuticals
OLMA

200 hedge funds and large institutions have $2.27B invested in Olema Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 87 funds opening new positions, 55 increasing their positions, 39 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

625% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 12

450% more funds holding in top 10

Funds holding in top 10: 2 → 11 (+9)

239% more capital invested

Capital invested by funds: $668M → $2.27B (+$1.6B)

76% more call options, than puts

Call options by funds: $30.8M | Put options by funds: $17.5M

59% more funds holding

Funds holding: 126 → 200 (+74)

41% more repeat investments, than reductions

Existing positions increased: 55 | Existing positions reduced: 39

32.66% more ownership

Funds ownership: 99.49% → 132.15% (+33%)

Holders
200
Holders Change
+74
Holders Change %
+58.73%
% of All Funds
2.43%
Holding in Top 10
11
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+450%
% of All Funds
0.13%
New
87
Increased
55
Reduced
39
Closed
12
Calls
$30.8M
Puts
$17.5M
Net Calls
+$13.3M
Net Calls Change
+$7.65M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$88.9M
2
SL
Siren LLC
Connecticut
+$58.7M
3
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$55.6M
4
CAM
Cormorant Asset Management
Massachusetts
+$48.9M
5
RCM
RA Capital Management
Massachusetts
+$46.3M

Top Sellers

1
DTC
Deep Track Capital
Connecticut
-$34M
2
Pictet Asset Management
Pictet Asset Management
Switzerland
-$20.2M
3
Ameriprise
Ameriprise
Minnesota
-$16.8M
4
UBS Group
UBS Group
Switzerland
-$16M
5
Morgan Stanley
Morgan Stanley
New York
-$15.8M
Name Holding Trade Value Shares
Change 		Change in
Stake
ACM
76
ADAR1 Capital Management
Texas
$2.03M +$804K +45,199 +125%
AQR Capital Management
77
AQR Capital Management
Connecticut
$2.03M -$249 -14 -0%
RhumbLine Advisers
78
RhumbLine Advisers
Massachusetts
$1.86M -$176K -9,910 -12%
SCM
79
Soleus Capital Management
Connecticut
$1.75M -$9.79M -550,000 -89%
SG Americas Securities
80
SG Americas Securities
New York
$1.74M +$1.23M +69,382 New
HIS
81
Harvest Investment Services
Illinois
$1.72M +$1.22M +68,723 New
NIP
82
Nicholas Investment Partners
California
$1.62M +$1.15M +64,757 New
Creative Planning
83
Creative Planning
Kansas
$1.62M +$166K +9,344 +17%
AA
84
ALPS Advisors
Colorado
$1.61M +$571K +32,082 +99%
FAM
85
Fred Alger Management
New York
$1.61M +$1.15M +64,484 New
Deutsche Bank
86
Deutsche Bank
Germany
$1.58M +$35.1K +1,975 +3%
AllianceBernstein
87
AllianceBernstein
Tennessee
$1.57M -$250K -14,050 -18%
QCM
88
Quantinno Capital Management
New York
$1.53M +$373K +20,976 +52%
LPL Financial
89
LPL Financial
California
$1.4M -$720K -40,480 -42%
Swedbank
90
Swedbank
Sweden
$1.38M +$980K +55,100 New
ACM
91
ACT Capital Management
Pennsylvania
$1.34M +$952K +53,500 New
PIC
92
Portland Investment Counsel
Ontario, Canada
$1.25M – – –
NAMI
93
Nomura Asset Management International
Pennsylvania
$1.25M +$890K +50,000 New
TI
94
Trexquant Investment
Connecticut
$1.24M +$885K +49,754 New
NIM
95
NEOS Investment Management
Connecticut
$1.13M +$804K +45,170 New
Rafferty Asset Management
96
Rafferty Asset Management
New York
$1.13M +$801K +45,005 New
TE
97
Tema ETFs
New York
$1.11M +$792K +44,505 New
VF
98
Virtu Financial
New York
$1.06M +$755K +42,437 New
Raymond James Financial
99
Raymond James Financial
Florida
$1.02M +$723K +40,647 New
BCM
100
Bridgeway Capital Management
Texas
$1.01M -$525K -29,500 -42%
2 3
4
5 6

OLMA Hedge Fund Activity: Q4 2025 in Review

200 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Olema Pharmaceuticals (OLMA) for Q4 2025, worth a combined $2.27B — up 239% from $668M a quarter earlier.

Buyers outnumbered sellers: 87 funds opened new OLMA positions and 12 closed out — a net gain of 75 holders — while 55 added to existing stakes and 39 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $88.9M. The largest seller was Deep Track Capital, exiting entirely with an estimated $34M sold.

  • 200 institutional investors held Olema Pharmaceuticals (OLMA) as of Q4 2025, up from 126 in Q3 2025.
  • Funds reported $2.27B of Olema Pharmaceuticals stock for Q4 2025, up 239% quarter-over-quarter.
  • 87 funds opened new Olema Pharmaceuticals positions in Q4 2025 and 12 closed out, a net change of +75 holders.
  • The largest Olema Pharmaceuticals buyer in Q4 2025 was Fidelity Investments, an estimated $88.9M added.
  • The largest Olema Pharmaceuticals seller in Q4 2025 was Deep Track Capital, an estimated $34M sold.

Based on aggregated 13F filings for Q4 2025.