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Olema Pharmaceuticals
OLMA

200 hedge funds and large institutions have $2.27B invested in Olema Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 87 funds opening new positions, 55 increasing their positions, 39 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

625% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 12

450% more funds holding in top 10

Funds holding in top 10: 2 → 11 (+9)

239% more capital invested

Capital invested by funds: $668M → $2.27B (+$1.6B)

76% more call options, than puts

Call options by funds: $30.8M | Put options by funds: $17.5M

59% more funds holding

Funds holding: 126 → 200 (+74)

41% more repeat investments, than reductions

Existing positions increased: 55 | Existing positions reduced: 39

32.66% more ownership

Funds ownership: 99.49% → 132.15% (+33%)

Holders
200
Holders Change
+74
Holders Change %
+58.73%
% of All Funds
2.43%
Holding in Top 10
11
Holding in Top 10 Change
+9
Holding in Top 10 Change %
+450%
% of All Funds
0.13%
New
87
Increased
55
Reduced
39
Closed
12
Calls
$30.8M
Puts
$17.5M
Net Calls
+$13.3M
Net Calls Change
+$7.65M

Top Buyers

1
Fidelity Investments
Fidelity Investments
Massachusetts
+$88.9M
2
SL
Siren LLC
Connecticut
+$58.7M
3
Janus Henderson Group
Janus Henderson Group
United Kingdom
+$55.6M
4
CAM
Cormorant Asset Management
Massachusetts
+$48.9M
5
RCM
RA Capital Management
Massachusetts
+$46.3M

Top Sellers

1
DTC
Deep Track Capital
Connecticut
-$34M
2
Pictet Asset Management
Pictet Asset Management
Switzerland
-$20.2M
3
Ameriprise
Ameriprise
Minnesota
-$16.8M
4
UBS Group
UBS Group
Switzerland
-$16M
5
Morgan Stanley
Morgan Stanley
New York
-$15.8M
Name Holding Trade Value Shares
Change 		Change in
Stake
Wellington Management Group
51
Wellington Management Group
Massachusetts
$5.52M +$298K +16,764 +8%
BFM
52
Boothbay Fund Management
New York
$5.48M +$3.9M +219,086 New
Adage Capital Partners
53
Adage Capital Partners
Massachusetts
$5.25M +$3.74M +210,000 New
SCM
54
Silverarc Capital Management
Massachusetts
$5.16M -$12.9M -727,261 -78%
Ameriprise
55
Ameriprise
Minnesota
$5.12M -$16.8M -942,439 -82%
Bank of New York Mellon
56
Bank of New York Mellon
New York
$4.41M +$125K +7,004 +4%
Balyasny Asset Management
57
Balyasny Asset Management
Illinois
$4.18M -$9.36M -525,871 -76%
PA
58
Perceptive Advisors
New York
$4.14M +$2.95M +165,713 New
Invesco
59
Invesco
Georgia
$3.89M +$553K +31,098 +25%
ECM
60
ExodusPoint Capital Management
New York
$3.77M +$2.68M +150,670 New
Citigroup
61
Citigroup
New York
$3.68M +$2.26M +126,917 +621%
PC
62
Pier Capital
Connecticut
$3.5M -$6.84M -384,148 -73%
TD Asset Management
63
TD Asset Management
Ontario, Canada
$3.41M +$2.43M +136,400 New
Barclays
64
Barclays
United Kingdom
$3.33M +$507K +28,501 +27%
BGM
65
Burkehill Global Management
New York
$3.13M +$2.22M +125,000 New
SPS
66
Susquehanna Portfolio Strategies
Pennsylvania
$3.03M – – –
SSA
67
Schonfeld Strategic Advisors
New York
$2.85M +$2.03M +113,978 New
BHCM
68
Brevan Howard Capital Management
Jersey
$2.7M +$1.92M +107,950 New
Manulife (Manufacturers Life Insurance)
69
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$2.56M +$1.46M +81,781 +398%
JF
70
Jump Financial
Illinois
$2.51M +$1.78M +100,274 New
RSCM
71
Rock Springs Capital Management
Maryland
$2.46M +$1.75M +98,240 New
SFI
72
Susquehanna Fundamental Investments
Pennsylvania
$2.37M – – –
American Century Companies
73
American Century Companies
Missouri
$2.35M +$621K +34,905 +59%
Victory Capital Management
74
Victory Capital Management
Texas
$2.15M -$36.5K -2,050 -2%
Wells Fargo
75
Wells Fargo
California
$2.1M +$685K +38,469 +84%
1 2
3
4 5

OLMA Hedge Fund Activity: Q4 2025 in Review

200 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in Olema Pharmaceuticals (OLMA) for Q4 2025, worth a combined $2.27B — up 239% from $668M a quarter earlier.

Buyers outnumbered sellers: 87 funds opened new OLMA positions and 12 closed out — a net gain of 75 holders — while 55 added to existing stakes and 39 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $88.9M. The largest seller was Deep Track Capital, exiting entirely with an estimated $34M sold.

  • 200 institutional investors held Olema Pharmaceuticals (OLMA) as of Q4 2025, up from 126 in Q3 2025.
  • Funds reported $2.27B of Olema Pharmaceuticals stock for Q4 2025, up 239% quarter-over-quarter.
  • 87 funds opened new Olema Pharmaceuticals positions in Q4 2025 and 12 closed out, a net change of +75 holders.
  • The largest Olema Pharmaceuticals buyer in Q4 2025 was Fidelity Investments, an estimated $88.9M added.
  • The largest Olema Pharmaceuticals seller in Q4 2025 was Deep Track Capital, an estimated $34M sold.

Based on aggregated 13F filings for Q4 2025.