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OKUR

OnKure Therapeutics

47 hedge funds and large institutions have $50.1M invested in OnKure Therapeutics in 2025 Q1 according to their latest regulatory filings, with 4 funds opening new positions, 15 increasing their positions, 13 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

15% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 13

0.1% more ownership

Funds ownership: 93.59%93.69% (+0.1%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

8% less funds holding

Funds holding: 5147 (-4)

49% less capital invested

Capital invested by funds: $99.2M → $50.1M (-$49.1M)

50% less first-time investments, than exits

New positions opened: 4 | Existing positions closed: 8

Holders
47
Holders Change
-4
Holders Change %
-7.84%
% of All Funds
0.63%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
4
Increased
15
Reduced
13
Closed
8
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
Renaissance Technologies
26
Renaissance Technologies
New York
$180K -$31.4K -5,587 -12%
Two Sigma Advisers
27
Two Sigma Advisers
New York
$119K +$75.4K +13,400 +94%
Two Sigma Investments
28
Two Sigma Investments
New York
$117K +$153K +27,148 New
BCM
29
Bridgeway Capital Management
Texas
$108K +$141K +25,000 New
Northern Trust
30
Northern Trust
Illinois
$82.5K
Qube Research & Technologies (QRT)
31
Qube Research & Technologies (QRT)
United Kingdom
$80.3K +$105K +18,663 New
ACM
32
ADAR1 Capital Management
Texas
$43K +$56.2K +10,000 New
Barclays
33
Barclays
United Kingdom
$29.1K -$11.1K -1,976 -23%
Wells Fargo
34
Wells Fargo
California
$15.6K +$11.2K +2,000 +123%
CUAMC
35
China Universal Asset Management Company
China
$10.9K -$815 -145 -5%
TRCT
36
Tower Research Capital (TRC)
New York
$9.56K +$129 +23 +1%
Morgan Stanley
37
Morgan Stanley
New York
$8.08K +$5.32K +946 +102%
Mirae Asset Global Investments
38
Mirae Asset Global Investments
South Korea
$1.89K +$6 +1 +0.2%
GFM
39
GF Fund Management
China
$1.35K +$264 +47 +18%
BNP Paribas Financial Markets
40
BNP Paribas Financial Markets
France
$1.28K +$343 +61 +26%
UBS Group
41
UBS Group
Switzerland
$1.2K -$10.9K -1,933 -87%
JP Morgan Chase
42
JP Morgan Chase
New York
$993 -$596 -106 -31%
Bank of America
43
Bank of America
North Carolina
$950 -$1.4M -249,421 -100%
Citigroup
44
Citigroup
New York
$818 +$495 +88 +86%
Group One Trading
45
Group One Trading
Illinois
$241 -$1.31K -233 -81%
MCM
46
MAI Capital Management
Ohio
$26
ACM
47
Altium Capital Management
New York
-$1.88M -218,386 Closed
Millennium Management
48
Millennium Management
New York
-$1.24M -144,099 Closed
6CM
49
683 Capital Management
New York
-$373K -43,371 Closed
CSS
50
Cubist Systematic Strategies
Connecticut
-$177K -20,549 Closed

OKUR Hedge Fund Activity: Q1 2025 in Review

47 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in OnKure Therapeutics (OKUR) for Q1 2025, worth a combined $50.1M — down 49% from $99.2M a quarter earlier.

Sellers outnumbered buyers: 8 funds closed out of OKUR and 4 opened new positions — a net loss of 4 holders — while 13 trimmed existing stakes and 15 added.

The largest buyer was Affinity Asset Advisors, adding an estimated $1.41M. The largest seller was Altium Capital Management, exiting entirely with an estimated $1.88M sold.

  • 47 institutional investors held OnKure Therapeutics (OKUR) as of Q1 2025, down from 51 in Q4 2024.
  • Funds reported $50.1M of OnKure Therapeutics stock for Q1 2025, down 49% quarter-over-quarter.
  • 4 funds opened new OnKure Therapeutics positions in Q1 2025 and 8 closed out, a net change of -4 holders.
  • The largest OnKure Therapeutics buyer in Q1 2025 was Affinity Asset Advisors, an estimated $1.41M added.
  • The largest OnKure Therapeutics seller in Q1 2025 was Altium Capital Management, an estimated $1.88M sold.

Based on aggregated 13F filings for Q1 2025.