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OKUR

OnKure Therapeutics

47 hedge funds and large institutions have $50.1M invested in OnKure Therapeutics in 2025 Q1 according to their latest regulatory filings, with 4 funds opening new positions, 15 increasing their positions, 13 reducing their positions, and 8 closing their positions.

New
Increased
Maintained
Reduced
Closed

15% more repeat investments, than reductions

Existing positions increased: 15 | Existing positions reduced: 13

0.1% more ownership

Funds ownership: 93.59%93.69% (+0.1%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

8% less funds holding

Funds holding: 5147 (-4)

49% less capital invested

Capital invested by funds: $99.2M → $50.1M (-$49.1M)

50% less first-time investments, than exits

New positions opened: 4 | Existing positions closed: 8

Holders
47
Holders Change
-4
Holders Change %
-7.84%
% of All Funds
0.63%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
4
Increased
15
Reduced
13
Closed
8
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
CAM
1
Cormorant Asset Management
Massachusetts
$7.9M
ACA
2
Acorn Capital Advisors
New York
$5.12M
Citadel Advisors
3
Citadel Advisors
Florida
$4.44M -$34.9K -6,210 -0.6%
PA
4
Perceptive Advisors
New York
$4.32M
SB
5
Samsara BioCapital
California
$3.54M
Vanguard Group
6
Vanguard Group
Pennsylvania
$3.04M
VPC
7
Vestal Point Capital
New York
$2.73M
DTC
8
Deep Track Capital
Connecticut
$2.25M
SG
9
StepStone Group
California
$2.12M
NMC
10
NEA Management Company
Maryland
$2.06M
HCM
11
Highbridge Capital Management
New York
$1.89M +$220K +39,054 +10%
TCM
12
Tang Capital Management
California
$1.72M +$593K +105,374 +36%
AAA
13
Affinity Asset Advisors
New York
$1.69M +$1.41M +250,000 +173%
CG
14
Carlyle Group
District of Columbia
$1.16M
IC
15
Ikarian Capital
Texas
$1.09M
PM
16
Prosight Management
Texas
$802K +$691K +122,816 +193%
SC
17
Shay Capital
New York
$649K +$765K +136,022 +906%
CF
18
Cantor Fitzgerald
New York
$562K +$534K +95,000 +266%
BlackRock
19
BlackRock
New York
$383K -$28.3K -5,036 -5%
ACM
20
Aisling Capital Management
New York
$381K
Geode Capital Management
21
Geode Capital Management
Massachusetts
$371K +$54.6K +9,712 +13%
SFM
22
Sphera Funds Management
Israel
$346K -$38.8K -6,900 -8%
BFM
23
Boothbay Fund Management
New York
$335K
NCM
24
Nantahala Capital Management
Connecticut
$233K -$3.2K -569 -1%
AC
25
Aldebaran Capital
Indiana
$194K -$2.95K -524 -1%

OKUR Hedge Fund Activity: Q1 2025 in Review

47 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in OnKure Therapeutics (OKUR) for Q1 2025, worth a combined $50.1M — down 49% from $99.2M a quarter earlier.

Sellers outnumbered buyers: 8 funds closed out of OKUR and 4 opened new positions — a net loss of 4 holders — while 13 trimmed existing stakes and 15 added.

The largest buyer was Affinity Asset Advisors, adding an estimated $1.41M. The largest seller was Altium Capital Management, exiting entirely with an estimated $1.88M sold.

  • 47 institutional investors held OnKure Therapeutics (OKUR) as of Q1 2025, down from 51 in Q4 2024.
  • Funds reported $50.1M of OnKure Therapeutics stock for Q1 2025, down 49% quarter-over-quarter.
  • 4 funds opened new OnKure Therapeutics positions in Q1 2025 and 8 closed out, a net change of -4 holders.
  • The largest OnKure Therapeutics buyer in Q1 2025 was Affinity Asset Advisors, an estimated $1.41M added.
  • The largest OnKure Therapeutics seller in Q1 2025 was Altium Capital Management, an estimated $1.88M sold.

Based on aggregated 13F filings for Q1 2025.