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Orchestra BioMed
OBIO

Overview Fund Activity

56 hedge funds and large institutions have $81.3M invested in Orchestra BioMed in 2025 Q1 according to their latest regulatory filings, with 7 funds opening new positions, 16 increasing their positions, 18 reducing their positions, and 4 closing their positions.

Holders
56
Holders Change
+2
Holders Change %
+3.7%
% of All Funds
0.76%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
7
Increased
16
Reduced
18
Closed
4
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
IA
1
IFP Advisors
Florida
$693K
2
NL
2
Nuveen LLC
North Carolina
$179K
3
State Street
3
State Street
Massachusetts
$2.03M
4
Geode Capital Management
4
Geode Capital Management
Massachusetts
$2.55M
5
Susquehanna International Group
5
Susquehanna International Group
Pennsylvania
$141K

Top Sellers

1
BCM
1
Boxer Capital Management
California
$0
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$51.2K
3
BlackRock
3
BlackRock
New York
$8.33M
4
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$1.97M
5
Millennium Management
5
Millennium Management
New York
$0
Name Market Value Shares Shares
Change 		Shares
Change %
RI
1
RTW Investments
New York
$35.1M 8,206,162 – –
PA
2
Perceptive Advisors
New York
$19.7M 4,592,556 – –
BlackRock
3
BlackRock
New York
$8.33M 1,945,656 -33,174 -2%
Vanguard Group
4
Vanguard Group
Pennsylvania
$5.6M 1,307,766 -9,804 -0.7%
Geode Capital Management
5
Geode Capital Management
Massachusetts
$2.55M 595,432 +22,991 +4%
State Street
6
State Street
Massachusetts
$2.03M 473,719 +26,007 +6%
T. Rowe Price Associates
7
T. Rowe Price Associates
Maryland
$1.97M 460,120 -27,050 -6%
Northern Trust
8
Northern Trust
Illinois
$1.02M 238,701 +1,940 +0.8%
Charles Schwab
9
Charles Schwab
California
$929K 216,985 -1,670 -0.8%
IA
10
IFP Advisors
Florida
$693K 161,921 +83,481 +106%
TD Asset Management
11
TD Asset Management
Ontario, Canada
$397K 92,678 – –
HighTower Advisors
12
HighTower Advisors
Illinois
$261K 61,000 -7,500 -11%
LM
13
Lasry Marc
$261K 60,869 – –
Bank of New York Mellon
14
Bank of New York Mellon
New York
$225K 52,490 -315 -0.6%
HIW
15
Holos Integrated Wealth
Pennsylvania
$221K 51,595 – –
Goldman Sachs
16
Goldman Sachs
New York
$209K 48,729 -13,408 -22%
Manulife (Manufacturers Life Insurance)
17
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$180K 41,984 +4,975 +13%
NL
18
Nuveen LLC
North Carolina
$179K 41,729 +41,729 New
Susquehanna International Group
19
Susquehanna International Group
Pennsylvania
$141K 32,988 +20,819 +171%
Morgan Stanley
20
Morgan Stanley
New York
$138K 32,134 -19,497 -38%
RhumbLine Advisers
21
RhumbLine Advisers
Massachusetts
$135K 31,657 +914 +3%
Barclays
22
Barclays
United Kingdom
$109K 25,609 -12,177 -32%
Citadel Advisors
23
Citadel Advisors
Florida
$87.7K 20,480 +8,201 +67%
Deutsche Bank
24
Deutsche Bank
Germany
$86.5K 20,219 +8,134 +67%
UBS Group
25
UBS Group
Switzerland
$73.9K 17,270 -6,795 -28%
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