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Orchestra BioMed

57 hedge funds and large institutions have $47.2M invested in Orchestra BioMed in 2025 Q2 according to their latest regulatory filings, with 21 funds opening new positions, 13 increasing their positions, 16 reducing their positions, and 19 closing their positions.

Holders
57
Holders Change
+1
Holders Change %
+1.79%
% of All Funds
0.77%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
21
Increased
13
Reduced
16
Closed
19
Calls
Puts
Net Calls
Net Calls Change
Name Market Value Shares Shares
Change
Shares
Change %
RI
1
RTW Investments
New York
$22.3M 8,306,062 +99,900 +1%
PA
2
Perceptive Advisors
New York
$12.3M 4,592,556
Vanguard Group
3
Vanguard Group
Pennsylvania
$3.1M 1,157,317 -150,449 -12%
BlackRock
4
BlackRock
New York
$1.83M 681,349 -1,264,307 -65%
T. Rowe Price Associates
5
T. Rowe Price Associates
Maryland
$1.18M 438,369 -21,751 -5%
Millennium Management
6
Millennium Management
New York
$1.1M 409,674 +409,674 New
Geode Capital Management
7
Geode Capital Management
Massachusetts
$810K 302,082 -293,350 -49%
Renaissance Technologies
8
Renaissance Technologies
New York
$454K 169,400 +169,400 New
Charles Schwab
9
Charles Schwab
California
$371K 138,591 -78,394 -36%
State Street
10
State Street
Massachusetts
$349K 130,133 -343,586 -73%
Northern Trust
11
Northern Trust
Illinois
$269K 100,435 -138,266 -58%
DMKJ
12
David M. Knott Jr
$268K 100,000 +100,000 New
Goldman Sachs
13
Goldman Sachs
New York
$260K 96,841 +48,112 +99%
TD Asset Management
14
TD Asset Management
Ontario, Canada
$248K 92,678
IA
15
IFP Advisors
Florida
$229K 85,358 -76,563 -47%
HighTower Advisors
16
HighTower Advisors
Illinois
$178K 66,500 +5,500 +9%
KCM
17
Knoll Capital Management
Florida
$170K 455,128 +455,128 New
LM
18
Lasry Marc
$163K 60,869
HIW
19
Holos Integrated Wealth
Pennsylvania
$140K 51,595
Marshall Wace
20
Marshall Wace
United Kingdom
$133K 49,465 +49,465 New
Citadel Advisors
21
Citadel Advisors
Florida
$133K 49,441 +28,961 +141%
YIH
22
Y-Intercept (HK)
Hong Kong
$122K 45,447 +45,447 New
NA
23
NewEdge Advisors
Louisiana
$118K 44,083 +44,083 New
Manulife (Manufacturers Life Insurance)
24
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$87.1K 32,518 -9,466 -23%
Squarepoint
25
Squarepoint
New York
$75.6K 28,221 +28,221 New