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Orchestra BioMed
OBIO

Overview Fund Activity

58 hedge funds and large institutions have $47.6M invested in Orchestra BioMed in 2025 Q2 according to their latest regulatory filings, with 21 funds opening new positions, 14 increasing their positions, 16 reducing their positions, and 19 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
58
Holders Change
+2
Holders Change %
+3.57%
% of All Funds
0.78%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.01%
New
21
Increased
14
Reduced
16
Closed
19
Calls
–
Puts
–
Net Calls
–
Net Calls Change
–

Top Buyers

1
Millennium Management
Millennium Management
New York
+$1.1M
2
Renaissance Technologies
Renaissance Technologies
New York
+$454K
3
DMKJ
David M. Knott Jr
+$268K
4
RI
RTW Investments
New York
+$268K
5
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$229K

Top Sellers

1
BlackRock
BlackRock
New York
-$3.39M
2
State Street
State Street
Massachusetts
-$921K
3
Geode Capital Management
Geode Capital Management
Massachusetts
-$786K
4
Vanguard Group
Vanguard Group
Pennsylvania
-$403K
5
Northern Trust
Northern Trust
Illinois
-$371K
Name Holding Trade Value Shares
Change 		Shares
Change %
JPMorgan Chase & Co
51
JPMorgan Chase & Co
New York
$1.26K -$30.8K -11,482 -96%
Carson Wealth (CWM LLC)
52
Carson Wealth (CWM LLC)
Nebraska
$1K +$874 +333 +694%
PD
53
Point72 (DIFC)
United Arab Emirates
$949 +$949 +354 New
Nisa Investment Advisors
54
Nisa Investment Advisors
Missouri
$646 -$1.51K -564 -70%
FFO
55
Fortitude Family Office
Arizona
$544 +$544 +203 New
Russell Investments Group
56
Russell Investments Group
United Kingdom
$517 +$517 +193 New
SO
57
Sierra Ocean
California
$319 – – –
EWA
58
EverSource Wealth Advisors
Alabama
$3 -$12 -4 -80%
Bank of New York Mellon
59
Bank of New York Mellon
New York
– -$225K -52,490 Closed
NL
60
Nuveen LLC
North Carolina
– -$179K -41,729 Closed
RhumbLine Advisers
61
RhumbLine Advisers
Massachusetts
– -$135K -31,657 Closed
Deutsche Bank
62
Deutsche Bank
Germany
– -$86.5K -20,219 Closed
IIM
63
INTECH Investment Management
Florida
– -$68.5K -16,002 Closed
Mirae Asset Global ETFs Holdings
64
Mirae Asset Global ETFs Holdings
Hong Kong
– -$64.4K -15,043 Closed
CF
65
Corebridge Financial
Texas
– -$51.5K -12,030 Closed
SEI Investments
66
SEI Investments
Pennsylvania
– -$44K -10,290 Closed
MCM
67
Massar Capital Management
Connecticut
– -$42.8K -10,000 Closed
PFSRSONJ
68
Police & Firemen's Retirement System of New Jersey
New Jersey
– -$20K -4,671 Closed
New York State Common Retirement Fund
69
New York State Common Retirement Fund
New York
– -$16K -3,623 Closed
Legal & General Group
70
Legal & General Group
United Kingdom
– -$9.52K -2,225 Closed
California State Teachers Retirement System (CalSTRS)
71
California State Teachers Retirement System (CalSTRS)
California
– -$8.1K -1,893 Closed
AIP
72
Ameritas Investment Partners
Nebraska
– -$5.98K -1,396 Closed
AB
73
Amalgamated Bank
New York
– -$4K -847 Closed
Northwestern Mutual Wealth Management
74
Northwestern Mutual Wealth Management
Wisconsin
– -$1.91K -447 Closed
SCM
75
Sterling Capital Management
North Carolina
– -$1.06K -247 Closed
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