|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$310M
|
+$239M
|
+4,202,059
|
+4,155%
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$184M
|
+$56.9M
|
+1,000,000
|
+64%
|
|
|
3
|
Two Seas Capital
Rye,
New York
|
$141M
|
+$69.1M
|
+1,213,993
|
+163%
|
|
|
4
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$86.1M
|
+$68.2M
|
+1,197,055
|
New
|
|
|
5
|
Two Sigma Investments
New York
|
$67M
|
+$26.1M
|
+457,727
|
+97%
|
|
|
6
|
Prosight Management
Dallas,
Texas
|
$52.9M
|
+$10.3M
|
+180,367
|
+33%
|
|
|
7
|
|
$49.8M
|
+$2.68M
|
+47,043
|
+7%
|
|
|
8
|
|
$47.4M
|
+$5.29M
|
+92,966
|
+16%
|
|
|
9
|
Armistice Capital
New York
|
$41.6M
|
-$1.02M
|
-18,000
|
-3%
|
|
|
10
|
|
$40.8M
|
+$5.65M
|
+99,299
|
+21%
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$36.9M
|
+$11.6M
|
+203,754
|
+66%
|
|
|
12
|
Sofinnova Investments
Menlo Park,
California
|
$36.7M
|
+$4.04M
|
+70,916
|
+16%
|
|
|
13
|
Woodline Partners
San Francisco,
California
|
$29.9M
|
+$17.7M
|
+311,335
|
+299%
|
|
|
14
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$29.1M
|
+$23.1M
|
+405,080
|
New
|
|
|
15
|
Millennium Management
New York
|
$29.1M
|
-$2.84M
|
-49,798
|
-11%
|
|
|
16
|
Emerald Advisers
Leola,
Pennsylvania
|
$28.4M
|
+$584K
|
+10,262
|
+3%
|
|
|
17
|
Qube Research & Technologies (QRT)
London,
United Kingdom
|
$28.1M
|
+$3.8M
|
+66,760
|
+21%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$25M
|
+$5.26M
|
+92,434
|
+36%
|
|
|
19
|
UBS Group
Zurich,
Switzerland
|
$23M
|
+$1.86M
|
+32,611
|
+11%
|
|
|
20
|
Great Point Partners
Greenwich,
Connecticut
|
$22.8M
|
+$6.02M
|
+105,721
|
+50%
|
|
|
21
|
Vestal Point Capital
New York
|
$20.5M
|
+$16.2M
|
+285,000
|
New
|
|
|
22
|
22NW LP
Seattle,
Washington
|
$20.2M
|
-$2.85M
|
-50,000
|
-15%
|
|
|
23
|
Primecap Management
Pasadena,
California
|
$20.1M
|
-$56.9K
|
-1,000
|
-0.4%
|
|
|
24
|
|
$19.8M
|
+$15.7M
|
+275,000
|
New
|
|
|
25
|
Gilder Gagnon Howe & Co
New York
|
$19.6M
|
+$3.61M
|
+63,456
|
+30%
|
|
