|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$354M
|
+$56M
|
+764,732
|
+18%
|
|
|
2
|
Two Seas Capital
Rye,
New York
|
$216M
|
+$82.9M
|
+1,133,056
|
+58%
|
|
|
3
|
|
$205M
|
+$165M
|
+2,249,201
|
+325%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$167M
|
-$12.3M
|
-168,520
|
-7%
|
|
|
5
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$104M
|
+$21.9M
|
+299,794
|
+25%
|
|
|
6
|
Two Sigma Investments
New York
|
$83.9M
|
+$19.8M
|
+271,263
|
+29%
|
|
|
7
|
Vestal Point Capital
New York
|
$69.8M
|
+$52.3M
|
+715,000
|
+251%
|
|
|
8
|
|
$65.4M
|
+$20.3M
|
+277,173
|
+42%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$63.5M
|
+$48.7M
|
+664,952
|
+272%
|
|
|
10
|
Geode Capital Management
Boston,
Massachusetts
|
$61.5M
|
+$39.1M
|
+534,511
|
+154%
|
|
|
11
|
Prosight Management
Dallas,
Texas
|
$56.5M
|
+$5.49M
|
+75,000
|
+10%
|
|
|
12
|
Armistice Capital
New York
|
$50.5M
|
+$10.7M
|
+146,000
|
+25%
|
|
|
13
|
Gilder Gagnon Howe & Co
New York
|
$41.9M
|
+$24.1M
|
+329,115
|
+121%
|
|
|
14
|
Millennium Management
New York
|
$33.4M
|
+$5.4M
|
+73,843
|
+18%
|
|
|
15
|
Braidwell
Stamford,
Connecticut
|
$33.1M
|
+$18.4M
|
+250,916
|
+113%
|
|
|
16
|
Sofinnova Investments
Menlo Park,
California
|
$32.9M
|
-$2.76M
|
-37,783
|
-7%
|
|
|
17
|
Woodline Partners
San Francisco,
California
|
$32.9M
|
+$4.06M
|
+55,540
|
+13%
|
|
|
18
|
|
$32.5M
|
+$13.9M
|
+190,346
|
+69%
|
|
|
19
|
UBS Group
Zurich,
Switzerland
|
$29.9M
|
+$7.92M
|
+108,228
|
+34%
|
|
|
20
|
Emerald Advisers
Leola,
Pennsylvania
|
$27.2M
|
-$325K
|
-4,446
|
-1%
|
|
|
21
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$26.6M
|
-$1.72M
|
-23,456
|
-6%
|
|
|
22
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$24.3M
|
+$20.2M
|
+276,049
|
+381%
|
|
|
23
|
DAFNA Capital Management
Los Angeles,
California
|
$22.2M
|
+$11.2M
|
+153,202
|
+93%
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$21.5M
|
+$16.8M
|
+229,933
|
+293%
|
|
|
25
|
Deep Track Capital
Greenwich,
Connecticut
|
$20.9M
|
+$22M
|
+300,000
|
New
|
|
