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Nektar Therapeutics

154 hedge funds and large institutions have $820M invested in Nektar Therapeutics in 2025 Q3 according to their latest regulatory filings, with 66 funds opening new positions, 43 increasing their positions, 27 reducing their positions, and 20 closing their positions.

New
Increased
Maintained
Reduced
Closed

315% more capital invested

Capital invested by funds: $198M → $820M (+$623M)

300% more funds holding in top 10

Funds holding in top 10: 14 (+3)

230% more first-time investments, than exits

New positions opened: 66 | Existing positions closed: 20

59% more repeat investments, than reductions

Existing positions increased: 43 | Existing positions reduced: 27

41% more funds holding

Funds holding: 109154 (+45)

14.09% more ownership

Funds ownership: 61.7%75.78% (+14%)

37% less call options, than puts

Call options by funds: $47.7M | Put options by funds: $75.6M

Holders
154
Holders Change
+45
Holders Change %
+41.28%
% of All Funds
2.02%
Holding in Top 10
4
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+300%
% of All Funds
0.05%
New
66
Increased
43
Reduced
27
Closed
20
Calls
$47.7M
Puts
$75.6M
Net Calls
-$27.9M
Net Calls Change
-$24.5M
Name Holding Trade Value Shares
Change
Change in
Stake
BI
1
BVF Inc
California
$72.6M +$42.3M +1,276,595 New
Vanguard Group
2
Vanguard Group
Pennsylvania
$54M +$7.25M +219,155 +30%
Morgan Stanley
3
Morgan Stanley
New York
$52.9M +$28.4M +857,012 +1,188%
Susquehanna International Group
4
Susquehanna International Group
Pennsylvania
$52.6M +$23.3M +703,005 +317%
FCM
5
Farallon Capital Management
California
$45M +$26.2M +791,000 New
BlackRock
6
BlackRock
New York
$34.7M +$6.42M +193,888 +47%
Millennium Management
7
Millennium Management
New York
$31.1M -$3.41M -103,039 -16%
Two Sigma Investments
8
Two Sigma Investments
New York
$24.7M +$11.7M +354,842 +447%
NCM
9
Nantahala Capital Management
Connecticut
$23.8M -$9.64M -291,239 -41%
Citadel Advisors
10
Citadel Advisors
Florida
$20.5M +$12M +361,073 New
2L
11
22NW LP
Washington
$18.8M +$6.12M +185,000 +127%
EA
12
Emerald Advisers
Pennsylvania
$18.4M +$10.7M +323,246 New
JFG
13
Jefferies Financial Group
New York
$17.3M +$10M +303,200 New
GPP
14
Great Point Partners
Connecticut
$17.1M +$9.93M +300,000 New
Primecap Management
15
Primecap Management
California
$16.4M -$353K -10,668 -4%
Renaissance Technologies
16
Renaissance Technologies
New York
$15.8M +$1.04M +31,481 +13%
AC
17
Armistice Capital
New York
$15.2M +$4.77M +144,000 +116%
EMFAT
18
Emerald Mutual Fund Advisers Trust
Pennsylvania
$13.3M +$7.72M +233,205 New
WP
19
Woodline Partners
California
$13.3M -$433K -13,086 -5%
Invesco
20
Invesco
Georgia
$12.9M +$6.45M +194,865 +608%
Geode Capital Management
21
Geode Capital Management
Massachusetts
$12.8M +$3.07M +92,863 +70%
GGHC
22
Gilder Gagnon Howe & Co
New York
$12.8M +$6.49M +195,926 +678%
Balyasny Asset Management
23
Balyasny Asset Management
Illinois
$10.4M -$6.73M -203,476 -53%
Two Sigma Advisers
24
Two Sigma Advisers
New York
$10.2M +$5.92M +178,908 New
Voloridge Investment Management
25
Voloridge Investment Management
Florida
$9.77M +$5.69M +171,776 New

NKTR Hedge Fund Activity: Q3 2025 in Review

154 of the 7,621 institutional investors tracked by Wall St. Rank reported a position in Nektar Therapeutics (NKTR) for Q3 2025, worth a combined $820M — up 315% from $198M a quarter earlier.

Buyers outnumbered sellers: 66 funds opened new NKTR positions and 20 closed out — a net gain of 46 holders — while 43 added to existing stakes and 27 trimmed.

The largest buyer was BVF Inc, opening a new position worth an estimated $42.3M. The largest seller was Acadian Asset Management, cutting an estimated $13M.

  • 154 institutional investors held Nektar Therapeutics (NKTR) as of Q3 2025, up from 109 in Q2 2025.
  • Funds reported $820M of Nektar Therapeutics stock for Q3 2025, up 315% quarter-over-quarter.
  • 66 funds opened new Nektar Therapeutics positions in Q3 2025 and 20 closed out, a net change of +46 holders.
  • The largest Nektar Therapeutics buyer in Q3 2025 was BVF Inc, an estimated $42.3M added.
  • The largest Nektar Therapeutics seller in Q3 2025 was Acadian Asset Management, an estimated $13M sold.

Based on aggregated 13F filings for Q3 2025.